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360 Zhang, W., Böttger, R., Qin, Z., Kulkarni, J. A., Vogler, J., Cullis, P. R., & Li, S.-D. (2019). Phospholipid-Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver. Small, 15(43), 1901782. doi:10.1002/smll.201901782

 

359 Ramezanpour, M., Schmidt, M. L., Bodnariuc, I., Kulkarni, J. A., Leung, S. S. W., Cullis, P. R., Thewalt, J. L., & Tieleman, D. P. (2019). Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function. Nanoscale, 11(30), 14141-14146. doi:10.1039/c9nr02297j

 

358 Kulkarni, J. A., Witzigmann, D., Leung, J., van der Meel, R., Zaifman, J., Darjuan, M. M., Grisch-Chan, H. M., Thony, B., Tam, Y. Y. C., & Cullis, P. R. (2019). Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale, 11(18), 9023-9031. doi:10.1039/c9nr02004g

 

357 Kulkarni, J. A., Witzigmann, D., Leung, J., Tam, Y. Y. C., & Cullis, P. R. (2019). On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale, 11(45), 21733-21739. doi:10.1039/c9nr09347h

 

356 Kulkarni, J. A., Witzigmann, D., Chen, S., Cullis, P. R., & van der Meel, R. (2019). Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics. Accounts of Chemical Research, 52(9), 2435-2444. doi:10.1021/acs.accounts.9b00368

 

355 Jyotsana, N., Sharma, A., Chaturvedi, A., Budida, R., Scherr, M., Kuchenbauer, F., Lindner, R., Noyan, F., Suhs, K. W., Stangel, M., Grote-Koska, D., Brand, K., Vornlocher, H. P., Eder, M., Thol, F., Ganser, A., Humphries, R. K., Ramsay, E., Cullis, P., & Heuser, M. (2019). Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Annals of Hematology, 98(8), 1905-1918. doi:10.1007/s00277-019-03713-y

 

354 Hamano, N., Bottger, R., Lee, S. E., Yang, Y., Kulkarni, J. A., Ip, S., Cullis, P. R., & Li, S. D. (2019). Robust Microfluidic Technology and New Lipid Composition for Fabrication of Curcumin-Loaded Liposomes: Effect on the Anticancer Activity and Safety of Cisplatin. Molecular Pharmaceutics, 16(9), 3957-3967. doi:10.1021/acs.molpharmaceut.9b00583

 

353 Buck, J., Grossen, P., Cullis, P. R., Huwyler, J., & Witzigmann, D. (2019). Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. ACS Nano, 13(4), 3754-3782. doi:10.1021/acsnano.8b07858

 

352 Bromma, K., Rieck, K., Kulkarni, J., O’Sullivan, C., Sung, W., Cullis, P., Schuemann, J., & Chithrani, D. B. (2019). Use of a lipid nanoparticle system as a Trojan horse in delivery of gold nanoparticles to human breast cancer cells for improved outcomes in radiation therapy. Cancer Nanotechnology, 10(1), 1. doi:10.1186/s12645-019-0046-z

 

351 Akinc, A., Maier, M. A., Manoharan, M., Fitzgerald, K., Jayaraman, M., Barros, S., Ansell, S., Du, X., Hope, M. J., Madden, T. D., Mui, B. L., Semple, S. C., Tam, Y. K., Ciufolini, M., Witzigmann, D., Kulkarni, J. A., van der Meel, R., & Cullis, P. R. (2019). The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs. Nature Nanotechnology, 14(12), 1084-1087. doi:10.1038/s41565-019-0591-y

 

350 Tang, W. L., Tang, W. H., Szeitz, A., Kulkarni, J., Cullis, P., & Li, S. D. (2018). Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery. Biomaterials, 166, 13-26. doi:10.1016/j.biomaterials.2018.03.004

 

349 Kulkarni, J. A., Darjuan, M. M., Mercer, J. E., Chen, S., van der Meel, R., Thewalt, J. L., Tam, Y. Y. C., & Cullis, P. R. (2018). On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. ACS Nano, 12(5), 4787-4795. doi:10.1021/acsnano.8b01516

 

348 Kulkarni, J. A., Cullis, P. R., & van der Meel, R. (2018). Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Therapeutics, 28(3), 146-157. doi:10.1089/nat.2018.0721

 

347 Jyotsana, N., Sharma, A., Chaturvedi, A., Scherr, M., Kuchenbauer, F., Sajti, L., Barchanski, A., Lindner, R., Noyan, F., Suhs, K. W., Grote-Koska, D., Brand, K., Vornlocher, H. P., Stanulla, M., Bornhauser, B., Bourquin, J. P., Eder, M., Thol, F., Ganser, A., Humphries, R. K., Ramsay, E., Cullis, P., & Heuser, M. (2018). RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo. Leukemia, 32(1), 224-226. doi:10.1038/leu.2017.269

 

346 Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P., & Schiffelers, R. M. (2018). State-of-the-Art Design and Rapid-Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery. Small Methods, 2(9), 1700375. doi:10.1002/smtd.201700375

 

345 Chen, S., Zaifman, J., Kulkarni, J. A., Zhigaltsev, I. V., Tam, Y. K., Ciufolini, M. A., Tam, Y. Y. C., & Cullis, P. R. (2018). Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids. Journal of Controlled Release, 286, 46-54. doi:10.1016/j.jconrel.2018.07.026

 

344 Cain, S. M., Tyson, J. R., Choi, H. B., Ko, R., Lin, P. J. C., LeDue, J. M., Powell, K. L., Bernier, L. P., Rungta, R. L., Yang, Y., Cullis, P. R., O'Brien, T. J., MacVicar, B. A., & Snutch, T. P. (2018). CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons. Epilepsia, 59(4), 778-791. doi:10.1111/epi.14018

 

343 Neumann, U. H., Ho, J. S. S., Chen, S., Tam, Y. Y. C., Cullis, P. R., & Kieffer, T. J. (2017). Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes. Molecular Metabolism, 6(10), 1161-1172. doi:10.1016/j.molmet.2017.06.012

 

342 Kulkarni, J. A., Tam, Y. Y. C., Chen, S., Tam, Y. K., Zaifman, J., Cullis, P. R., & Biswas, S. (2017). Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles. Nanoscale, 9(36), 13600-13609. doi:10.1039/c7nr03272b

 

341 Kulkarni, J. A., Myhre, J. L., Chen, S., Tam, Y. Y. C., Danescu, A., Richman, J. M., & Cullis, P. R. (2017). Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine, 13(4), 1377-1387. doi:10.1016/j.nano.2016.12.014

 

340 Cullis, P. R., & Hope, M. J. (2017). Lipid Nanoparticle Systems for Enabling Gene Therapies. Molecular Therapy, 25(7), 1467-1475. doi:10.1016/j.ymthe.2017.03.013

 

339 Zhigaltsev, I. V., Tam, Y. K., Leung, A. K., & Cullis, P. R. (2016). Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents. Journal of Liposome Research, 26(2), 96-102. doi:10.3109/08982104.2015.1025411

 

338 Wang, H., Tam, Y. Y., Chen, S., Zaifman, J., van der Meel, R., Ciufolini, M. A., & Cullis, P. R. (2016). The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA. Molecular Therapy, 24(12), 2100-2108. doi:10.1038/mt.2016.179

 

337 Lee, J. B., Zhang, K., Tam, Y. Y., Quick, J., Tam, Y. K., Lin, P. J., Chen, S., Liu, Y., Nair, J. K., Zlatev, I., Rajeev, K. G., Manoharan, M., Rennie, P. S., & Cullis, P. R. (2016). A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo. Molecular Therapy: Nucleic Acids, 5, e348. doi:10.1038/mtna.2016.43

 

336 Chen, S., Tam, Y. Y. C., Lin, P. J. C., Sung, M. M. H., Tam, Y. K., & Cullis, P. R. (2016). Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA. Journal of Controlled Release, 235, 236-244. doi:10.1016/j.jconrel.2016.05.059

 

335 Basha, G., Ordobadi, M., Scott, W. R., Cottle, A., Liu, Y., Wang, H., & Cullis, P. R. (2016). Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo. Molecular Therapy: Nucleic Acids, 5(9), e363. doi:10.1038/mtna.2016.68

 

334 Yamamoto, Y., Lin, P. J., Beraldi, E., Zhang, F., Kawai, Y., Leong, J., Katsumi, H., Fazli, L., Fraser, R., Cullis, P. R., & Gleave, M. (2015). siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays Progression When Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer. Clinical Cancer Research, 21(21), 4845-4855. doi:10.1158/1078-0432.Ccr-15-0866

 

333 Rungta, R. L., Choi, H. B., Tyson, J. R., Malik, A., Dissing-Olesen, L., Lin, P. J. C., Cain, S. M., Cullis, P. R., Snutch, T. P., & MacVicar, B. A. (2015). The cellular mechanisms of neuronal swelling underlying cytotoxic edema. Cell, 161(3), 610-621. doi:10.1016/j.cell.2015.03.029

 

332 Ramishetti, S., Kedmi, R., Goldsmith, M., Leonard, F., Sprague, A. G., Godin, B., Gozin, M., Cullis, P. R., Dykxhoorn, D. M., & Peer, D. (2015). Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles. ACS Nano, 9(7), 6706-6716. doi:10.1021/acsnano.5b02796

 

331 Leung, A. K., Tam, Y. Y., Chen, S., Hafez, I. M., & Cullis, P. R. (2015). Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems. Journal of Physical Chemistry B, 119(28), 8698-8706. doi:10.1021/acs.jpcb.5b02891

 

330 Wan, C., Allen, T. M., & Cullis, P. R. (2014). Lipid nanoparticle delivery systems for siRNA-based therapeutics. Drug delivery and translational research, 4(1), 74-83. doi:10.1007/s13346-013-0161-z

 

329 Walsh, C., Ou, K., Belliveau, N. M., Leaver, T. J., Wild, A. W., Huft, J., Lin, P. J., Chen, S., Leung, A. K., Lee, J. B., Hansen, C. L., Taylor, R. J., Ramsay, E. C., & Cullis, P. R. (2014). Microfluidic-based manufacture of siRNA-lipid nanoparticles for therapeutic applications. Methods in Molecular Biology, 1141, 109-120. doi:10.1007/978-1-4939-0363-4_6

 

328 Neumann, U. H., Chen, S., Tam, Y. Y., Baker, R. K., Covey, S. D., Cullis, P. R., & Kieffer, T. J. (2014). IGFBP2 is neither sufficient nor necessary for the physiological actions of leptin on glucose homeostasis in male ob/ob mice. Endocrinology, 155(3), 716-725. doi:10.1210/en.2013-1622

 

327 Lin, P. J., Tam, Y. K., & Cullis, P. R. (2014). Development and clinical applications of siRNA-encapsulated lipid nanoparticles in cancer. Clinical Lipidology, 9(3), 317-331. doi:10.2217/clp.14.27

 

326 Leung, A. K., Tam, Y. Y., & Cullis, P. R. (2014). Lipid nanoparticles for short interfering RNA delivery. Advances in Genetics, 88, 71-110. doi:10.1016/b978-0-12-800148-6.00004-3

 

325 Fenske, D. B., & Cullis, P. R. (2014). Chapter 15 - Medical Applications of Lipid Nanoparticles. In Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application (1 ed.). Boca Raton: CRC Press.

 

324 Chen, S., Tam, Y. Y., Lin, P. J., Leung, A. K., Tam, Y. K., & Cullis, P. R. (2014). Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration. Journal of Controlled Release, 196, 106-112. doi:10.1016/j.jconrel.2014.09.025

 

323 Tam, Y. Y. C., Chen, S., & Cullis, P. R. (2013). Advances in Lipid Nanoparticles for siRNA Delivery. Pharmaceutics, 5(3), 498-507. doi:10.3390/pharmaceutics5030498

 

322 Tam, Y. Y., Chen, S., Zaifman, J., Tam, Y. K., Lin, P. J., Ansell, S., Roberge, M., Ciufolini, M. A., & Cullis, P. R. (2013). Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA. Nanomedicine, 9(5), 665-674. doi:10.1016/j.nano.2012.11.006

 

321 Rungta, R. L., Choi, H. B., Lin, P. J., Ko, R. W., Ashby, D., Nair, J., Manoharan, M., Cullis, P. R., & Macvicar, B. A. (2013). Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain. Molecular Therapy: Nucleic Acids, 2, e136. doi:10.1038/mtna.2013.65

 

320 Mui, B. L., Tam, Y. K., Jayaraman, M., Ansell, S. M., Du, X., Tam, Y. Y., Lin, P. J., Chen, S., Narayanannair, J. K., Rajeev, K. G., Manoharan, M., Akinc, A., Maier, M. A., Cullis, P., Madden, T. D., & Hope, M. J. (2013). Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles. Molecular Therapy: Nucleic Acids, 2, e139. doi:10.1038/mtna.2013.66

 

319 Maier, M. A., Jayaraman, M., Matsuda, S., Liu, J., Barros, S., Querbes, W., Tam, Y. K., Ansell, S. M., Kumar, V., Qin, J., Zhang, X., Wang, Q., Panesar, S., Hutabarat, R., Carioto, M., Hettinger, J., Kandasamy, P., Butler, D., Rajeev, K. G., Pang, B., Charisse, K., Fitzgerald, K., Mui, B. L., Du, X., Cullis, P., Madden, T. D., Hope, M. J., Manoharan, M., & Akinc, A. (2013). Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. Molecular Therapy, 21(8), 1570-1578. doi:10.1038/mt.2013.124

 

318 Lin, P. J., Tam, Y. Y., Hafez, I., Sandhu, A., Chen, S., Ciufolini, M. A., Nabi, I. R., & Cullis, P. R. (2013). Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA. Nanomedicine, 9(2), 233-246. doi:10.1016/j.nano.2012.05.019

 

317 Allen, T. M., & Cullis, P. R. (2013). Liposomal drug delivery systems: From concept to clinical applications. Advanced Drug Delivery Reviews, 65(1), 36-48. doi:10.1016/j.addr.2012.09.037

 

316 Zhigaltsev, I. V., Belliveau, N. M., Hafez, I., Leung, A. K. K., Huft, J., Hansen, C. L., & Cullis, P. R. (2012). Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing. Langmuir, 28(7), 3633-3640. doi:10.1021/la204833h

 

315 Novobrantseva, T. I., Borodovsky, A., Wong, J., Klebanov, B., Zafari, M., Yucius, K., Querbes, W., Ge, P., Ruda, V. M., Milstein, S., Speciner, L., Duncan, R., Barros, S., Basha, G., Cullis, P., Akinc, A., Donahoe, J. S., Narayanannair Jayaprakash, K., Jayaraman, M., Bogorad, R. L., Love, K., Whitehead, K., Levins, C., Manoharan, M., Swirski, F. K., Weissleder, R., Langer, R., Anderson, D. G., de Fougerolles, A., Nahrendorf, M., & Koteliansky, V. (2012). Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Molecular Therapy: Nucleic Acids, 1, e4. doi:10.1038/mtna.2011.3

 

314 Leung, A. K., Hafez, I. M., Baoukina, S., Belliveau, N. M., Zhigaltsev, I. V., Afshinmanesh, E., Tieleman, D. P., Hansen, C. L., Hope, M. J., & Cullis, P. R. (2012). Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core. Journal of Physical Chemistry C: Nanomaterials and Interfaces, 116(34), 18440-18450. doi:10.1021/jp303267y

 

313 Lee, J. B., Zhang, K., Tam, Y. Y., Tam, Y. K., Belliveau, N. M., Sung, V. Y., Lin, P. J., LeBlanc, E., Ciufolini, M. A., Rennie, P. S., & Cullis, P. R. (2012). Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo. International Journal of Cancer, 131(5), E781-E790. doi:10.1002/ijc.27361

 

312 Jayaraman, M., Ansell, S. M., Mui, B. L., Tam, Y. K., Chen, J., Du, X., Butler, D., Eltepu, L., Matsuda, S., Narayanannair, J. K., Rajeev, K. G., Hafez, I. M., Akinc, A., Maier, M. A., Tracy, M. A., Cullis, P. R., Madden, T. D., Manoharan, M., & Hope, M. J. (2012). Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo. Angewandte Chemie International Edition in English, 51(34), 8529-8533. doi:10.1002/anie.201203263

 

311 Belliveau, N. M., Huft, J., Lin, P. J., Chen, S., Leung, A. K., Leaver, T. J., Wild, A. W., Lee, J. B., Taylor, R. J., Tam, Y. K., Hansen, C. L., & Cullis, P. R. (2012). Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA. Molecular Therapy: Nucleic Acids, 1, e37. doi:10.1038/mtna.2012.28

 

310 Geetha-Loganathan, P., Nimmagadda, S., Hafez, I., Fu, K., Cullis, P. R., & Richman, J. M. (2011). Development of high-concentration lipoplexes for in vivo gene function studies in vertebrate embryos. Developmental Dynamics, 240(9), 2108-2119. doi:10.1002/dvdy.22708

 

309 Basha, G., Novobrantseva, T. I., Rosin, N., Tam, Y. Y., Hafez, I. M., Wong, M. K., Sugo, T., Ruda, V. M., Qin, J., Klebanov, B., Ciufolini, M., Akinc, A., Tam, Y. K., Hope, M. J., & Cullis, P. R. (2011). Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells. Molecular Therapy, 19(12), 2186-2200. doi:10.1038/mt.2011.190

 

308 Zhigaltsev, I. V., Winters, G., Srinivasulu, M., Crawford, J., Wong, M., Amankwa, L., Waterhouse, D., Masin, D., Webb, M., Harasym, N., Heller, L., Bally, M. B., Ciufolini, M. A., Cullis, P. R., & Maurer, N. (2010). Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles. Journal of Controlled Release, 144(3), 332-340. doi:10.1016/j.jconrel.2010.02.029

 

307 Semple, S. C., Akinc, A., Chen, J., Sandhu, A. P., Mui, B. L., Cho, C. K., Sah, D. W., Stebbing, D., Crosley, E. J., Yaworski, E., Hafez, I. M., Dorkin, J. R., Qin, J., Lam, K., Rajeev, K. G., Wong, K. F., Jeffs, L. B., Nechev, L., Eisenhardt, M. L., Jayaraman, M., Kazem, M., Maier, M. A., Srinivasulu, M., Weinstein, M. J., Chen, Q., Alvarez, R., Barros, S. A., De, S., Klimuk, S. K., Borland, T., Kosovrasti, V., Cantley, W. L., Tam, Y. K., Manoharan, M., Ciufolini, M. A., Tracy, M. A., de Fougerolles, A., MacLachlan, I., Cullis, P. R., Madden, T. D., & Hope, M. J. (2010). Rational design of cationic lipids for siRNA delivery. Nature Biotechnology, 28(2), 172-176. doi:10.1038/nbt.1602

 

306 de Jong, S. D., Basha, G., Wilson, K. D., Kazem, M., Cullis, P., Jefferies, W., & Tam, Y. (2010). The Immunostimulatory Activity of Unmethylated and Methylated CpG Oligodeoxynucleotide Is Dependent on Their Ability To Colocalize with TLR9 in Late Endosomes. The Journal of Immunology, 184(11), 6092-6102. doi:10.4049/jimmunol.0802442

 

305 Wilson, K. D., de Jong, S. D., Kazem, M., Lall, R., Hope, M. J., Cullis, P. R., & Tam, Y. K. (2009). The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine. Journal of Gene Medicine, 11(1), 14-25. doi:10.1002/jgm.1267

 

304 Cressman, S., Sun, Y., Maxwell, E. J., Fang, N., Chen, D. D. Y., & Cullis, P. R. (2009). Binding and Uptake of RGD-Containing Ligands to Cellular αvβ3 Integrins. International Journal of Peptide Research and Therapeutics, 15(1), 49-59. doi:10.1007/s10989-008-9163-y

 

303 Cressman, S., Dobson, I., Lee, J. B., Tam, Y. Y. C., & Cullis, P. R. (2009). Synthesis of a Labeled RGD−Lipid, Its Incorporation into Liposomal Nanoparticles, and Their Trafficking in Cultured Endothelial Cells. Bioconjugate Chemistry, 20(7), 1404-1411. doi:10.1021/bc900041f

 

302 Chikh, G., de Jong, S. D., Sekirov, L., Raney, S. G., Kazem, M., Wilson, K. D., Cullis, P. R., Dutz, J. P., & Tam, Y. K. (2009). Synthetic methylated CpG ODNs are potent in vivo adjuvants when delivered in liposomal nanoparticles. International Immunology, 21(7), 757-767. doi:10.1093/intimm/dxp044

 

301 Sun, Y., Cressman, S., Fang, N., Cullis, P. R., & Chen, D. D. Y. (2008). Capillary Electrophoresis Frontal Analysis for Characterization of αvβ3 Integrin Binding Interactions. Analytical Chemistry, 80(9), 3105-3111. doi:10.1021/ac701604a

 

300 Raney, S. G., Wilson, K. D., Sekirov, L., Chikh, G., de Jong, S. D., Cullis, P. R., & Tam, Y. K. (2008). The effect of circulation lifetime and drug-to-lipid ratio of intravenously administered lipid nanoparticles on the biodistribution and immunostimulatory activity of encapsulated CpG-ODN. Journal of Drug Targeting, 16(7), 564-577. doi:10.1080/10611860802228756

 

299 Johnston, M. J., Edwards, K., Karlsson, G., & Cullis, P. R. (2008). Influence of drug-to-lipid ratio on drug release properties and liposome integrity in liposomal doxorubicin formulations. Journal of Liposome Research, 18(2), 145-157. doi:10.1080/08982100802129372

 

298 Fenske, D. B., & Cullis, P. R. (2008). Liposomal nanomedicines. Expert Opinion on Drug Delivery, 5(1), 25-44. doi:10.1517/17425247.5.1.25

 

297 Fenske, D. B., Chonn, A., & Cullis, P. R. (2008). Liposomal nanomedicines: an emerging field. Toxicologic Pathology, 36(1), 21-29. doi:10.1177/0192623307310960

 

296 Wilson, K. D., Raney, S. G., Sekirov, L., Chikh, G., de Jong, S. D., Cullis, P. R., & Tam, Y. K. (2007). Effects of intravenous and subcutaneous administration on the pharmacokinetics, biodistribution, cellular uptake and immunostimulatory activity of CpG ODN encapsulated in liposomal nanoparticles. International immunopharmacology, 7(8), 1064-1075. doi:10.1016/j.intimp.2007.04.002

 

295 Webb, M. S., Boman, N. L., Masin, D., Yapp, D., Ramsay, E., Chiu, G. N. C., Cullis, P. R., & Bally, M. B. (2007). A Cationic Liposomal Vincristine Formulation with Improved Vincristine Retention, Extended Circulation Lifetime and Increased Anti-Tumor Activity. Letters in Drug Design & Discovery, 4(6), 426-433. doi:10.2174/157018007781387782  
294 Maurer, N., Zhigaltsev, I., & Cullis, P. R. (2007). Encapsulation of Nucleic Acid–Based Therapeutics. In G. Gregoriadis (Ed.), Liposome Technology: Entrapment of Drugs and Other Materials into Liposomes (3 ed., Vol. 2, pp. 131-148). Boca Raton: CRC Press.

 

293 Johnston, M. J., Semple, S. C., Klimuk, S. K., Ansell, S., Maurer, N., & Cullis, P. R. (2007). Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin. Biochimica et biophysica acta, 1768(5), 1121-1127. doi:10.1016/j.bbamem.2007.01.019

 

292 Fenske, D. B., & Cullis, P. R. (2007). Encapsulation of Drugs Within Liposomes by pH-Gradient Techniques. In G. Gregoriadis (Ed.), Liposome Technology: Entrapment of Drugs and Other Materials into Liposomes (3 ed., Vol. 2, pp. 27-50). Boca Raton: CRC Press.

 

291 de Jonge, J., Leenhouts, J. M., Holtrop, M., Schoen, P., Scherrer, P., Cullis, P. R., Wilschut, J., & Huckriede, A. (2007). Cellular gene transfer mediated by influenza virosomes with encapsulated plasmid DNA. Biochemical Journal, 405(1), 41-49. doi:10.1042/bj20061756

 

290 de Jong, S., Chikh, G., Sekirov, L., Raney, S., Semple, S., Klimuk, S., Yuan, N., Hope, M., Cullis, P., & Tam, Y. (2007). Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN. Cancer Immunology, Immunotherapy, 56(8), 1251-1264. doi:10.1007/s00262-006-0276-x

 

289 Zhigaltsev, I. V., Maurer, N., Edwards, K., Karlsson, G., & Cullis, P. R. (2006). Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention. Journal of Controlled Release, 110(2), 378-386. doi:10.1016/j.jconrel.2005.10.011

 

288 Johnston, M. J., Semple, S. C., Klimuk, S. K., Edwards, K., Eisenhardt, M. L., Leng, E. C., Karlsson, G., Yanko, D., & Cullis, P. R. (2006). Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations. Biochimica et biophysica acta, 1758(1), 55-64. doi:10.1016/j.bbamem.2006.01.009

 

287 Zhigaltsev, I. V., Maurer, N., Akhong, Q. F., Leone, R., Leng, E., Wang, J., Semple, S. C., & Cullis, P. R. (2005). Liposome-encapsulated vincristine, vinblastine and vinorelbine: a comparative study of drug loading and retention. Journal of Controlled Release, 104(1), 103-111. doi:10.1016/j.jconrel.2005.01.010

 

286 Waterhouse, D. N., Madden, T. D., Cullis, P. R., Bally, M. B., Mayer, L. D., & Webb, M. S. (2005). Preparation, characterization, and biological analysis of liposomal formulations of vincristine. Methods in Enzymology, 391, 40-57. doi:10.1016/s0076-6879(05)91002-1

 

285 Semple, S. C., Leone, R., Wang, J., Leng, E. C., Klimuk, S. K., Eisenhardt, M. L., Yuan, Z. N., Edwards, K., Maurer, N., Hope, M. J., Cullis, P. R., & Ahkong, Q. F. (2005). Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity. Journal of Pharmaceutical Sciences, 94(5), 1024-1038. doi:10.1002/jps.20332

 

284 Sandhu, A. P., Lam, A. M., Fenske, D. B., Palmer, L. R., Johnston, M., & Cullis, P. R. (2005). Calcium enhances the transfection potency of stabilized plasmid-lipid particles. Analytical Biochemistry, 341(1), 156-164. doi:10.1016/j.ab.2005.02.033

 

283 Maclachlan, I., & Cullis, P. R. (2005). Diffusible-PEG-Lipid Stabilized Plasmid Lipid Particles. Advances in Genetics, 53pa, 157-188. doi:10.1016/s0065-2660(05)53006-2

 

282 Finn, J. D., Wong, T., & Cullis, P. R. (2005). Investigation of factors responsible for cell line cytoplasmic expression differences. BMC Molecular and Cell Biology, 6(1), 11. doi:10.1186/1471-2199-6-11

 

281 Finn, J., MacLachlan, I., & Cullis, P. (2005). Factors limiting autogene-based cytoplasmic expression systems. FASEB Journal, 19(6), 608-610. doi:10.1096/fj.04-2769fje

 

280 Fenske, D. B., & Cullis, P. R. (2005). Entrapment of small molecules and nucleic acid-based drugs in liposomes. Methods in Enzymology, 391, 7-40. doi:10.1016/s0076-6879(05)91001-x

 

279 Ambegia, E., Ansell, S., Cullis, P., Heyes, J., Palmer, L., & MacLachlan, I. (2005). Stabilized plasmid-lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression. Biochimica et biophysica acta, 1669(2), 155-163. doi:10.1016/j.bbamem.2005.02.001

 

278 Abraham, S. A., Waterhouse, D. N., Mayer, L. D., Cullis, P. R., Madden, T. D., & Bally, M. B. (2005). The liposomal formulation of doxorubicin. Methods in Enzymology, 391, 71-97. doi:10.1016/s0076-6879(05)91004-5

 

277 Hafez, I. M., & Cullis, P. R. (2004). Tunable pH-sensitive liposomes. Methods in Enzymology, 387, 113-134. doi:10.1016/s0076-6879(04)87007-1

 

276 Finn, J., Lee, A. C., MacLachlan, I., & Cullis, P. (2004). An enhanced autogene-based dual-promoter cytoplasmic expression system yields increased gene expression. Gene Therapy, 11(3), 276-283. doi:10.1038/sj.gt.3302172

 

275 Fenske, D. B., & Cullis, P. R. (2004). Liposomes: Models of Biological Membranes and Drug Delivery Systems. Physics in Canada, 60(2), 187-194.

 

274 Chen, T., Palmer, L. R., Fenske, D. B., Lam, A. M., Wong, K. F., & Cullis, P. R. (2004). Distal cationic poly(ethylene glycol) lipid conjugates in large unilamellar vesicles prepared by extrusion enhance liposomal cellular uptake. Journal of Liposome Research, 14(3-4), 155-173. doi:10.1081/lpr-200033437

 

273 Chen, T., McIntosh, D., He, Y. H., Kim, J. S., Tirrell, D. A., Scherrer, P., Fenske, D. B., Sandhu, A. P., & Cullis, P. R. (2004). Alkylated derivatives of poly(ethylacrylic acid) can be inserted into preformed liposomes and trigger pH-dependent intracellular delivery of liposomal contents. Molecular Membrane Biology, 21(6), 385-393. doi:10.1080/09687860400010516

 

272 Allen, T. M., & Cullis, P. R. (2004). Drug delivery systems: entering the mainstream. Science, 303(5665), 1818-1822. doi:10.1126/science.1095833

 

271 Palmer, L. R., Chen, T., Lam, A. M., Fenske, D. B., Wong, K. F., MacLachlan, I., & Cullis, P. R. (2003). Transfection properties of stabilized plasmid-lipid particles containing cationic PEG lipids. Biochimica et biophysica acta, 1611(1-2), 204-216. doi:10.1016/s0005-2736(03)00058-0

 

270 Zhigaltsev, I. V., Maurer, N., Wong, K. F., & Cullis, P. R. (2002). Triggered release of doxorubicin following mixing of cationic and anionic liposomes. Biochimica et biophysica acta, 1565(1), 129-135. doi:10.1016/s0005-2736(02)00543-6

 

269 Gaucheron, J., Wong, T., Wong, K. F., Maurer, N., & Cullis, P. R. (2002). Synthesis and Properties of Novel Tetraalkyl Cationic Lipids. Bioconjugate Chemistry, 13(3), 671-675. doi:10.1021/bc0101259

 

268 Fenske, D. B., MacLachlan, I., & Cullis, P. R. (2002). Stabilized plasmid-lipid particles: a systemic gene therapy vector. Methods in Enzymology, 346, 36-71. doi:10.1016/s0076-6879(02)46048-x

 

267 Cullis, P. R. (2002). Stabilized plasmid-lipid particles for systemic gene therapy. Cellular & Molecular Biology Letters, 7(2), 226.

 

266 Semple, S. C., Klimuk, S. K., Harasym, T. O., Dos Santos, N., Ansell, S. M., Wong, K. F., Maurer, N., Stark, H., Cullis, P. R., Hope, M. J., & Scherrer, P. (2001). Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures. Biochimica et biophysica acta, 1510(1-2), 152-166. doi:10.1016/s0005-2736(00)00343-6

 

265 Maurer, N., Wong, K. F., Stark, H., Louie, L., McIntosh, D., Wong, T., Scherrer, P., Semple, S. C., & Cullis, P. R. (2001). Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes. Biophysical journal, 80(5), 2310-2326. doi:10.1016/s0006-3495(01)76202-9

 

264 Maurer, N., Fenske, D. B., & Cullis, P. R. (2001). Developments in liposomal drug delivery systems. Expert Opinion on Biological Therapy, 1(6), 923-947. doi:10.1517/14712598.1.6.923

 

263 Hafez, I. M., Maurer, N., & Cullis, P. R. (2001). On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids. Gene Therapy, 8(15), 1188-1196. doi:10.1038/sj.gt.3301506

 

262 Hafez, I. M., & Cullis, P. R. (2001). Roles of lipid polymorphism in intracellular delivery. Advanced Drug Delivery Reviews, 47(2-3), 139-148. doi:10.1016/s0169-409x(01)00103-x

 

261 Fenske, D. B., Palmer, L. R., Chen, T., Wong, K. F., & Cullis, P. R. (2001). Cationic poly(ethyleneglycol) lipids incorporated into pre-formed vesicles enhance binding and uptake to BHK cells. Biochimica et biophysica acta, 1512(2), 259-272. doi:10.1016/s0005-2736(01)00327-3

 

260 Fenske, D. B., MacLachlan, I., & Cullis, P. R. (2001). Long-circulating vectors for the systemic delivery of genes. Current Opinion in Molecular Therapeutics, 3(2), 153-158. Retrieved from http://europepmc.org/abstract/MED/11338928

 

259 Webb, M. S., Sarris, A. H., Cabanillas, F., Mayer, L. D., Bally, M. B., Burge, C., & Cullis, P. R. (2000). Clinical and Preclinical Pharmacology of Liposomal Vincristine. Journal of Liposome Research, 10(4), 501-512. doi:10.3109/08982100009031114

 

258 Tam, P., Monck, M., Lee, D., Ludkovski, O., Leng, E. C., Clow, K., Stark, H., Scherrer, P., Graham, R. W., & Cullis, P. R. (2000). Stabilized plasmid-lipid particles for systemic gene therapy. Gene Therapy, 7(21), 1867-1874. doi:10.1038/sj.gt.3301308

 

257 Scherrer, P., Maurer, N., Monck, M., Saravolac, E., Zhang, Y. P., Wheeler, J., Tam, P., Lam, A., & Cullis, P. R. (2000). Design and Properties of a Lipid-Based Carrier System for Systemic Gene Therapy. In G. Gregoriadis & B. McCormack (Eds.), Targeting of Drugs: Strategies for Gene Constructs and Delivery (Vol. 323, pp. 165-185). Amsterdam, Washington, D. C.: IOS Press.

 

256 Saravolac, E. G., Ludkovski, O., Skirrow, R., Ossanlou, M., Zhang, Y. P., Giesbrecht, C., Thompson, J., Thomas, S., Stark, H., Cullis, P. R., & Scherrer, P. (2000). Encapsulation of plasmid DNA in stabilized plasmid-lipid particles composed of different cationic lipid concentration for optimal transfection activity. Journal of Drug Targeting, 7(6), 423-437. doi:10.3109/10611860009102217

 

255 Oja, C., Tardi, P., Schutze-Redelmeier, M., & Cullis, P. R. (2000). Doxorubicin entrapped within liposome-associated antigens results in a selective inhibition of the antibody response to the linked antigen. Biochimica et biophysica acta, 1468(1-2), 31-40. doi:10.1016/s0005-2736(00)00178-4

 

254 Monck, M. A., Mori, A., Lee, D., Tam, P., Wheeler, J. J., Cullis, P. R., & Scherrer, P. (2000). Stabilized Plasmid–Lipid Particles: Pharmacokinetics and Plasmid Delivery to Distal Tumors following Intravenous Injection. Journal of Drug Targeting, 7(6), 439-452. doi:10.3109/10611860009102218

 

253 MacLachlan, I., Cullis, P. R., & Graham, R. W. (2000). Synthetic Virus Systems for Systemic Gene Therapy. In N. S. Templeton & D. D. Lasic (Eds.), Gene Therapy: Therapeutic Mechanisms and Strategies (pp. 267-290). New York: Marcel Dekker Inc.

 

252 Lam, A. M., & Cullis, P. R. (2000). Calcium enhances the transfection potency of plasmid DNA-cationic liposome complexes. Biochimica et biophysica acta, 1463(2), 279-290. doi:10.1016/s0005-2736(99)00219-9

 

251 Huang, Y. Y., Maurer, N., & Cullis, P. R. (2000). Developing serum-stabilized cationic liposome-dna particles for gene therapy by preformed vesicles and ethanol method. Biomedical Engineering: Applications, Basis and Communications, 12, 217-222.  
250 Hafez, I. M., & Cullis, P. R. (2000). Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior. Biochimica et biophysica acta, 1463(1), 107-114. doi:10.1016/s0005-2736(99)00186-8

 

249 Hafez, I. M., Ansell, S., & Cullis, P. R. (2000). Tunable pH-sensitive liposomes composed of mixtures of cationic and anionic lipids. Biophysical journal, 79(3), 1438-1446. doi:10.1016/S0006-3495(00)76395-8

 

248 Cullis, P. R., & Huang, Y. Y. (2000). Transfection of BHK cell by serum-stabilized cationic liposome-DNA particles. Biomedical Engineering: Applications, Basis and Communications, 12(6), 281-287.  
247 Cullis, P. R. (2000). Commentary: Liposomes by Accident. Journal of Liposome Research, 10(2-3), ix-xxiv. doi:10.3109/08982100009029380

 

246 Chen, T., Wong, K. F., Fenske, D. B., Palmer, L. R., & Cullis, P. R. (2000). Fluorescent-labeled poly(ethylene glycol) lipid conjugates with distal cationic headgroups. Bioconjugate Chemistry, 11(3), 433-437. doi:10.1021/bc990171x

 

245 Ansell, S. M., Harasym, T. O., Tardi, P. G., Buchkowsky, S. S., Bally, M. B., & Cullis, P. R. (2000). Antibody conjugation methods for active targeting of liposomes. Methods In Molecular Medicine, 25, 51-68. doi:10.1385/1-59259-075-6:51

 

244 Zhang, Y. P., Sekirov, L., Saravolac, E. G., Wheeler, J. J., Tardi, P., Clow, K., Leng, E., Sun, R., Cullis, P. R., & Scherrer, P. (1999). Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties. Gene Therapy, 6(8), 1438-1447. doi:10.1038/sj.gt.3300965

 

243 Wheeler, J. J., Palmer, L., Ossanlou, M., MacLachlan, I., Graham, R. W., Zhang, Y. P., Hope, M. J., Scherrer, P., & Cullis, P. R. (1999). Stabilized plasmid-lipid particles: construction and characterization. Gene Therapy, 6(2), 271-281. doi:10.1038/sj.gt.3300821

 

242 Schoen, P., Chonn, A., Cullis, P. R., Wilschut, J., & Scherrer, P. (1999). Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles. Gene Therapy, 6(5), 823-832. doi:10.1038/sj.gt.3300919

 

241 Mok, K. W., Lam, A. M., & Cullis, P. R. (1999). Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties. Biochimica et biophysica acta, 1419(2), 137-150. doi:10.1016/s0005-2736(99)00059-0

 

240 Maurer-Spurej, E., Wong, K. F., Maurer, N., Fenske, D. B., & Cullis, P. R. (1999). Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochimica et biophysica acta, 1416(1-2), 1-10. doi:10.1016/s0005-2736(98)00204-1

 

239 Maurer, N., Mori, A., Palmer, L., Monck, M. A., Mok, K. W., Mui, B., Akhong, Q. F., & Cullis, P. R. (1999). Lipid-based systems for the intracellular delivery of genetic drugs. Molecular Membrane Biology, 16(1), 129-140. doi:10.1080/096876899294869

 

238 MacLachlan, I., Cullis, P., & Graham, R. W. (1999). Progress towards a synthetic virus for systemic gene therapy. Current Opinion in Molecular Therapeutics, 1(2), 252-259

 

237 Chen, T., Choi, L. S., Einstein, S., Klippenstein, M. A., Scherrer, P., & Cullis, P. R. (1999). Proton-Induced Permeability and Fusion of Large Unilamellar Vesicles by Covalently Conjugated Poly(2-Ethylacrylic Acid). Journal of Liposome Research, 9(3), 387-405. doi:10.3109/08982109909018658

 

236 Webb, M. S., Saxon, D., Wong, F. M., Lim, H. J., Wang, Z., Bally, M. B., Choi, L. S., Cullis, P. R., & Mayer, L. D. (1998). Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine. Biochimica et biophysica acta, 1372(2), 272-282. doi:10.1016/s0005-2736(98)00077-7

 

235 Semple, S. C., Chonn, A., & Cullis, P. R. (1998). Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo. Advanced Drug Delivery Reviews, 32(1-2), 3-17. doi:10.1016/s0169-409x(97)00128-2

 

234 Schmid, S. L., & Cullis, P. R. (1998). Membrane sorting. Endosome marker is fat not fiction. Nature, 392(6672), 135-136. doi:10.1038/32309

 

233 Mori, A., Chonn, A., Choi, L. S., Israels, A., Monck, M. A., & Cullis, P. R. (1998). Stabilization and Regulated Fusion of Liposomes Containing a Cationic Lipid Using Amphipathic Polyethyleneglycol Derivatives. Journal of Liposome Research, 8(2), 195-211. doi:10.3109/08982109809035526

 

232 Mayer, L. D., Cullis, P. R., & Bally, M. B. (1998). Chapter 4.2 - Designing therapeutically optimized liposomal anticancer delivery systems: Lessons from conventional liposomes. In D. D. Lasic & D. Papahadjopoulos (Eds.), Medical Applications of Liposomes (pp. 231-257). Amsterdam: Elsevier Science B.V.  
231 Maurer, N., Wong, K. F., Hope, M. J., & Cullis, P. R. (1998). Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a 1H-NMR study. Biochimica et biophysica acta, 1374(1-2), 9-20. doi:10.1016/s0005-2736(98)00125-4

 

230 Fenske, D. B., Wong, K. F., Maurer, E., Maurer, N., Leenhouts, J. M., Boman, N., Amankwa, L., & Cullis, P. R. (1998). Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients. Biochimica et biophysica acta, 1414(1-2), 188-204. doi:10.1016/s0005-2736(98)00166-7

 

229 Chonn, A., & Cullis, P. R. (1998). Recent advances in liposome technologies and their applications for systemic gene delivery. Advanced Drug Delivery Reviews, 30(1-3), 73-83. doi:10.1016/s0169-409x(97)00108-7

 

228 Cheung, B. C., Sun, T. H., Leenhouts, J. M., & Cullis, P. R. (1998). Loading of doxorubicin into liposomes by forming Mn2+-drug complexes. Biochimica et biophysica acta, 1414(1-2), 205-216. doi:10.1016/s0005-2736(98)00168-0

 

227 Boman, N. L., Cullis, P. R., Mayer, L. D., Bally, M. B., & Webb, M. S. (1998). Liposomal Vincristine: The Central Role of Drug Retention in Defining Therapeutically Optimized Anticancer Formulations. In M. C. Woodle & G. Storm (Eds.), Long Circulating Liposomes: Old Drugs, New Therapeutics (pp. 29-49). Berlin, Heidelberg: Springer Berlin Heidelberg

 

226 Bally, M. B., Lim, H., Cullis, P. R., & Mayer, L. D. (1998). Controlling the Drug Delivery Attributes of Lipid-Based Drug Formulations. Journal of Liposome Research, 8(3), 299-335. doi:10.3109/08982109809035537

 

225 Tardi, P. G., Swartz, E. N., Harasym, T. O., Cullis, P. R., & Bally, M. B. (1997). An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin. Journal of Immunological Methods, 210(2), 137-148. doi:10.1016/s0022-1759(97)00178-6

 

224 Parr, M. J., Masin, D., Cullis, P. R., & Bally, M. B. (1997). Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol). Journal of Pharmacology and Experimental Therapeutics, 280(3), 1319-1327

 

223 Mok, K. W., & Cullis, P. R. (1997). Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA. Biophysical journal, 73(5), 2534-2545. doi:10.1016/S0006-3495(97)78282-1

 

222 Harasym, T. O., Cullis, P. R., & Bally, M. B. (1997). Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes. Cancer Chemotherapy and Pharmacology, 40(4), 309-317. doi:10.1007/s002800050662

 

221 Felgner, P. L., Barenholz, Y., Behr, J. P., Cheng, S. H., Cullis, P. R., Huang, L., Jessee, J. A., Seymour, L., Szoka, F., Thierry, A. R., Wagner, E., & Wu, G. (1997). Nomenclature for Synthetic Gene Delivery Systems. Human Gene Therapy, 8(5), 511-512. doi:10.1089/hum.1997.8.5-511  
220 Cullis, P. R., Hope, M. J., Bally, M. B., Madden, T. D., Mayer, L. D., & Fenske, D. B. (1997). Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles. Biochimica et biophysica acta, 1331(2), 187-211. doi:10.1016/s0304-4157(97)00006-3

 

219 Bailey, A. L., Monck, M. A., & Cullis, P. R. (1997). pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin. Biochimica et biophysica acta, 1324(2), 232-244. doi:10.1016/s0005-2736(96)00228-3

 

218 Bailey, A. L., & Cullis, P. R. (1997). Membrane fusion with cationic liposomes: effects of target membrane lipid composition. Biochemistry, 36(7), 1628-1634. doi:10.1021/bi961173x

 

217 Bailey, A. L., & Cullis, P. R. (1997). Chapter 9 - Liposome Fusion. In R. M. Epand (Ed.), Current Topics in Membranes (Vol. 44, pp. 359-373): Academic Press

 

216 Tardi, P. G., Boman, N. L., & Cullis, P. R. (1996). Liposomal doxorubicin. Journal of Drug Targeting, 4(3), 129-140. doi:10.3109/10611869609015970

 

215 Semple, S. C., Chonn, A., & Cullis, P. R. (1996). Influence of cholesterol on the association of plasma proteins with liposomes. Biochemistry, 35(8), 2521-2525. doi:10.1021/bi950414i

 

214 Oja, C. D., Semple, S. C., Chonn, A., & Cullis, P. R. (1996). Influence of dose on liposome clearance: critical role of blood proteins. Biochimica et biophysica acta, 1281(1), 31-37. doi:10.1016/0005-2736(96)00003-x

 

213 Lafleur, M., Bloom, M., Eikenberry, E. F., Gruner, S. M., Han, Y., & Cullis, P. R. (1996). Correlation between lipid plane curvature and lipid chain order. Biophysical journal, 70(6), 2747-2757. doi:10.1016/S0006-3495(96)79844-2

 

212 Holland, J. W., Hui, C., Cullis, P. R., & Madden, T. D. (1996). Poly(ethylene glycol)-lipid conjugates regulate the calcium-induced fusion of liposomes composed of phosphatidylethanolamine and phosphatidylserine. Biochemistry, 35(8), 2618-2624. doi:10.1021/bi952000v

 

211 Holland, J. W., Cullis, P. R., & Madden, T. D. (1996). Poly(ethylene glycol)-lipid conjugates promote bilayer formation in mixtures of non-bilayer-forming lipids. Biochemistry, 35(8), 2610-2617. doi:10.1021/bi951999j

 

210 Fenske, D. B., & Cullis, P. R. (1996). Lipid Polymorphism. In The Encyclopedia of Nuclear Magnetic Resonance (pp. 2730-2735). New York: John Wiley & Sons

 

209 Cullis, P. R., Fenske, D. B., & Hope, M. J. (1996). Chapter 1 - Physical properties and functional roles of lipids in membranes. In D. E. Vance & J. E. Vance (Eds.), New Comprehensive Biochemistry (Vol. 31, pp. 1-33): Elsevier

 

208 Boman, N. L., Tron, V. A., Bally, M. B., & Cullis, P. R. (1996). Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes. Cancer Chemotherapy and Pharmacology, 37(4), 351-355. doi:10.1007/s002800050396

 

207 Mui, B. L., Döbereiner, H. G., Madden, T. D., & Cullis, P. R. (1995). Influence of transbilayer area asymmetry on the morphology of large unilamellar vesicles. Biophysical journal, 69(3), 930-941. doi:10.1016/S0006-3495(95)79967-2

 

206 Longman, S. A., Tardi, P. G., Parr, M. J., Choi, L., Cullis, P. R., & Bally, M. B. (1995). Accumulation of protein-coated liposomes in an extravascular site: influence of increasing carrier circulation lifetimes. Journal of Pharmacology and Experimental Therapeutics, 275(3), 1177-1184

 

205 Longman, S. A., Cullis, P. R., Choi, L., de Jong, G., & Bally, M. B. (1995). A two-step targeting approach for delivery of doxorubicin-loaded liposomes to tumour cells in vivo. Cancer Chemotherapy and Pharmacology, 36(2), 91-101. doi:10.1007/bf00689191

 

204 Longman, S. A., Cullis, P. R., & Bally, M. B. (1995). A model approach for assessing liposome targeting in vivo. Drug Delivery, 2(3-4), 156-165. doi:10.3109/10717549509031365

 

203 Harasym, T. O., Tardi, P., Longman, S. A., Ansell, S. M., Bally, M. B., Cullis, P. R., & Choi, L. S. (1995). Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes. Bioconjugate Chemistry, 6(2), 187-194. doi:10.1021/bc00032a006

 

202 Fenske, D. B., Monck, M. A., Cullis, P. R., & Hope, M. J. (1995). The functional roles of lipids in biological membranes. In A. G. lee (Ed.), Biomembranes: A Multi-Volume Treatise (Vol. 1, pp. 1-28): JAI

 

201 Cullis, P. R., & Hope, M. J. (1995). Liposomes, dimitri papahadjopoulos, and us. Journal of Liposome Research, 5(4), 829-836. doi:10.3109/08982109509012684

 

200 Chonn, A., Semple, S. C., & Cullis, P. R. (1995). β2-Glycoprotein I Is a Major Protein Associated with Very Rapidly Cleared Liposomes in Vivo, Suggesting a Significant Role in the Immune Clearance of "Non-self" Particles. Journal of Biological Chemistry, 270(43), 25845-25849. doi:10.1074/jbc.270.43.25845

 

199 Chonn, A., & Cullis, P. R. (1995). Recent advances in liposomal drug-delivery systems. Current Opinion in Biotechnology, 6(6), 698-708. doi:10.1016/0958-1669(95)80115-4

 

198 Boman, N. L., Cullis, P. R., Bally, M. B., & Mayer, L. D. (1995). Preclinical and Clinical Activity of Liposomal Doxorubicin. In Liposomes in Biomedical Applications (pp. 85-103): Harwood Academic Publishers

 

197 Boman, N. L., Bally, M. B., Cullis, P. R., Mayer, L. D., & Webb, M. S. (1995). Encapsulation of Vincristine in Liposomes Reduces its Toxicity and Improves its Anti-Tumor Efficacy. Journal of Liposome Research, 5(3), 523-541. doi:10.3109/08982109509010240

 

196 Wheeler, J. J., Veiro, J. A., & Cullis, P. R. (1994). Ionophore-mediated loading of Ca 2+ into large unilamellar vesicles in response to transmembrane pH gradients. Molecular Membrane Biology, 11(3), 151-157. doi:10.3109/09687689409162233

 

195 Parr, M. J., Ansell, S. M., Choi, L. S., & Cullis, P. R. (1994). Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles. Biochimica et biophysica acta, 1195(1), 21-30. doi:10.1016/0005-2736(94)90004-3

 

194 Mui, B. L., Cullis, P. R., Pritchard, P. H., & Madden, T. D. (1994). Influence of plasma on the osmotic sensitivity of large unilamellar vesicles prepared by extrusion. Journal of Biological Chemistry, 269(10), 7364-7370

 

193 Mayer, L. D., Cullis, P. R., & Bally, M. B. (1994). The Use of Transmembrane pH Gradient-Driven Drug Encapsulation in the Pharmacodynamic Evaluation of Liposomal Doxorubicin. Journal of Liposome Research, 4(1), 529-553. doi:10.3109/08982109409037060

 

192 Lewis, R. N., McElhaney, R. N., Monck, M. A., & Cullis, P. R. (1994). Studies of highly asymmetric mixed-chain diacyl phosphatidylcholines that form mixed-interdigitated gel phases: Fourier transform infrared and 2H NMR spectroscopic studies of hydrocarbon chain conformation and orientational order in the liquid-crystalline state. Biophysical journal, 67(1), 197-207. doi:10.1016/s0006-3495(94)80470-9

 

191 Devine, D. V., Wong, K., Serrano, K., Chonn, A., & Cullis, P. R. (1994). Liposome-complement interactions in rat serum: implications for liposome survival studies. Biochimica et biophysica acta, 1191(1), 43-51. doi:10.1016/0005-2736(94)90231-3

 

190 Chonn, A., Semple, S. C., & Cullis, P. R. (1994). Protein-Membrane Interactions in the Complex Biological Milieu. In Biological Membranes: Structure, Biogenesis and Dynamics (pp. 101-106). Berlin, Heidelberg: Springer

 

189 Chakrabarti, A. C., Clark-Lewis, I., & Cullis, P. R. (1994). Influence of Charge, Charge Distribution, and Hydrophobicity on the Transport of Short Model Peptides into Liposomes in Response to Transmembrane pH Gradients. Biochemistry, 33(28), 8479-8485. doi:10.1021/bi00194a012

 

188 Boman, N. L., Masin, D., Mayer, L. D., Cullis, P. R., & Bally, M. B. (1994). Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors. Cancer Research, 54(11), 2830-2833

 

187 Bally, M. B., Masin, D., Nayar, R., Cullis, P. R., & Mayer, L. D. (1994). Transfer of liposomal drug carriers from the blood to the peritoneal cavity of normal and ascitic tumor-bearing mice. Cancer Chemotherapy and Pharmacology, 34(2), 137-146. doi:10.1007/BF00685931

 

186 Bailey, A. L., & Cullis, P. R. (1994). Modulation of Membrane Fusion by Asymmetric Transbilayer Distributions of Amino Lipids. Biochemistry, 33(42), 12573-12580. doi:10.1021/bi00208a007

 

185 Parr, M. J., Bally, M. B., & Cullis, P. R. (1993). The presence of GM1 in liposomes with entrapped doxorubicin does not prevent RES blockade. Biochimica et biophysica acta, 1168(2), 249-252. doi:10.1016/0005-2760(93)90132-s

 

184 Mui, B. L., Cullis, P. R., Evans, E. A., & Madden, T. D. (1993). Osmotic properties of large unilamellar vesicles prepared by extrusion. Biophysical journal, 64(2), 443-453. doi:10.1016/S0006-3495(93)81385-7

 

183 Monck, M. A., Bloom, M., Lafleur, M., Lewis, R. N. A. H., McElhaney, R. N., & Cullis, P. R. (1993). Evidence for two pools of cholesterol in the Acholeplasma laidlawii strain B membrane: A deuterium NMR and DSC study. Biochemistry, 32(12), 3081-3088. doi:10.1021/bi00063a020

 

182 Mayer, L. D., Nayar, R., Thies, R. L., Boman, N. L., Cullis, P. R., & Bally, M. B. (1993). Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia. Cancer Chemotherapy and Pharmacology, 33(1), 17-24. doi:10.1007/bf00686017

 

181 Mayer, L. D., Madden, T. D., Bally, M. B., & Cullis, P. R. (1993). pH Gradient-Mediated Drug Entrapment in Liposomes. In Liposome Technology: Entrapment of Drugs and Other Materials (2 ed., Vol. 2, pp. 27-44)  
180 Loughrey, H. C., Choi, L. S., Wong, K. F., Cullis, P. R., & Bally, M. B. (1993). Preparation of Streptavidin-Liposomes for Use in Ligand-Specific Targeting Applications. In Liposome Technology: Interactions of Liposomes with the Biological Milieu (2 ed., Vol. 3, pp. 163-178)

 

179 Kanter, P. M., Bullard, G. A., Pilkiewicz, F. G., Mayer, L. D., Cullis, P. R., & Pavelic, Z. P. (1993). Preclinical toxicology study of liposome encapsulated doxorubicin (TLC D-99): comparison with doxorubicin and empty liposomes in mice and dogs. In Vivo, 7(1), 85-95  
178 Hope, M. J., Nayar, R., Mayer, L. D., & Cullis, P. R. (1993). Reduction of Liposome Size and Preparation of Unilamellar Vesicles by Extrusion Techniques. In Liposome Technology: Liposome Preparation and Related Techniques (2 ed., Vol. 1, pp. 123). Boca Raton, FL: CRC Press, Inc.

 

177 Harrigan, P. R., Wong, K. F., Redelmeier, T. E., Wheeler, J. J., & Cullis, P. R. (1993). Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients. Biochimica et biophysica acta, 1149(2), 329-338. doi:10.1016/0005-2736(93)90218-o

 

176 Fenske, D. B., & Cullis, P. R. (1993). Acyl chain orientational order in large unilamellar vesicles: comparison with multilamellar liposomes: a 2H and 31P nuclear magnetic resonance study. Biophysical journal, 64(5), 1482-1491. doi:10.1016/S0006-3495(93)81515-7

 

175 Embree, L., Gelmon, K. A., Lohr, A., Mayer, L. D., Coldman, A. J., Cullis, P. R., Palaitis, W., Pilkiewicz, F. G., Hudon, N. J., Heggie, J. R., & Goldie, J. H. (1993). Chromatographic Analysis and Pharmacokinetics of Liposome-Encapsulated Doxorubicin in Non-Small-Cell Lung Cancer Patients. Journal of Pharmaceutical Sciences, 82(6), 627-634. doi:10.1002/jps.2600820617  
174 Boman, N. L., Mayer, L. D., & Cullis, P. R. (1993). Optimization of the retention properties of vincristine in liposomal systems. Biochimica et biophysica acta, 1152(2), 253-258. doi:10.1016/0005-2736(93)90256-Y

 

173 Wilschut, J., Scholma, J., Eastman, S. J., Hope, M. J., & Cullis, P. R. (1992). Ca(2+)-induced fusion of phospholipid vesicles containing free fatty acids: modulation by transmembrane pH gradients. Biochemistry, 31(10), 2629-2636. doi:10.1021/bi00125a001

 

172 Monck, M. A., Bloom, M., Lafleur, M., Lewis, R. N. A. H., McElhaney, R. N., & Cullis, P. R. (1992). Influence of lipid composition on the orientational order in Acholeplasma laidlawii strain B membranes: A deuterium NMR study. Biochemistry, 31(41), 10037-10043. doi:10.1021/bi00156a025

 

171 Kitson, N., Monck, M. A., Wong, K., Thewalt, J., & Cullis, P. R. (1992). The influence of cholesterol 3-sulphate on phase behaviour and hydrocarbon order in model membrane systems. Biochimica et biophysica acta, 1111(1), 127-133. doi:10.1016/0005-2736(92)90282-Q

 

170 Harrigan, P. R., Hope, M. J., Redelmeier, T. E., & Cullis, P. R. (1992). Determination of transmembrane pH gradients and membrane potentials in liposomes. Biophysical journal, 63(5), 1336-1345. doi:10.1016/S0006-3495(92)81711-3

 

169 Fenske, D. B., & Cullis, P. R. (1992). Chemical exchange between lamellar and non-lamellar lipid phases. A one- and two-dimensional 31P-NMR study. Biochimica et biophysica acta, 1108(2), 201-209. doi:10.1016/0005-2736(92)90026-I

 

168 Eastman, S. J., Hope, M. J., Wong, K. F., & Cullis, P. R. (1992). Influence of phospholipid asymmetry on fusion between large unilamellar vesicles. Biochemistry, 31(17), 4262-4268. doi:10.1021/bi00132a016

 

167 Chonn, A., Semple, S. C., & Cullis, P. R. (1992). Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes. Journal of Biological Chemistry, 267(26), 18759-18765.

 

166 Chonn, A., & Cullis, P. R. (1992). Ganglioside GM1 and Hydrophilic Polymers Increase Liposome Circulation Times by Inhibiting the Association of Blood Proteins. Journal of Liposome Research, 2(3), 397-410. doi:10.3109/08982109209010217

 

165 Chakrabarti, A. C., Veiro, J. A., Wong, N. S., Wheeler, J. J., & Cullis, P. R. (1992). Generation and characterization of iron- and barium-loaded liposomes. Biochimica et biophysica acta, 1108(2), 233-239. doi:10.1016/0005-2736(92)90030-P

 

164 Chakrabarti, A. C., Clark-Lewis, I., Harrigan, P. R., & Cullis, P. R. (1992). Uptake of basic amino acids and peptides into liposomes in response to transmembrane pH gradients. Biophysical journal, 61(1), 228-234. doi:10.1016/S0006-3495(92)81829-5

 

163 Eastman, S. J., Hope, M. J., & Cullis, P. R. (1991). Transbilayer transport of phosphatidic acid in response to transmembrane pH gradients. Biochemistry, 30(7), 1740-1745. doi:10.1021/bi00221a002

 

162 Cullis, P. R., Bally, M. B., Madden, T. D., Mayer, L. D., & Hope, M. J. (1991). pH gradients and membrane transport in liposomal systems. Trends in Biotechnology, 9(1), 268-272. doi:10.1016/0167-7799(91)90088-Y

 

161 Chonn, A., Semple, S. C., & Cullis, P. R. (1991). Separation of large unilamellar liposomes from blood components by a spin column procedure: towards identifying plasma proteins which mediate liposome clearance in vivo. Biochimica et biophysica acta, 1070(1), 215-222. doi:10.1016/0005-2736(91)90167-7

 

160 Chonn, A., Cullis, P. R., & Devine, D. V. (1991). The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes. The Journal of Immunology, 146(12), 4234-4241

 

159 Veiro, J. A., & Cullis, P. R. (1990). A novel method for the efficient entrapment of calcium in large unilamellar phospholipid vesicles. Biochimica et biophysica acta, 1025(1), 109-115. doi:10.1016/0005-2736(90)90197-V

 

158 Thies, R. L., Cowens, D. W., Cullis, P. R., Bally, M. B., & Mayer, L. D. (1990). Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma. Analytical Biochemistry, 188(1), 65-71. doi:10.1016/0003-2697(90)90528-h

 

157 Redelmeier, T. E., Hope, M. J., & Cullis, P. R. (1990). On the mechanism of transbilayer transport of phosphatidylglycerol in response to transmembrane pH gradients. Biochemistry, 29(12), 3046-3053. doi:10.1021/bi00464a022

 

156 Mayer, L. D., Tai, L. C., Bally, M. B., Mitilenes, G. N., Ginsberg, R. S., & Cullis, P. R. (1990). Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients. Biochimica et biophysica acta, 1025(2), 143-151. doi:10.1016/0005-2736(90)90091-2

 

155 Mayer, L. D., Bally, M. B., Loughrey, H., Masin, D., & Cullis, P. R. (1990). Liposomal vincristine preparations which exhibit decreased drug toxicity and increased activity against murine L1210 and P388 tumors. Cancer Research, 50(3), 575-579

 

154 Mayer, L. D., Bally, M. B., Cullis, P. R., Wilson, S. L., & Emerman, J. T. (1990). Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mammary tumor. Cancer Letters, 53(2-3), 183-190. doi:10.1016/0304-3835(90)90212-g

 

153 Mayer, L. D., Bally, M. B., & Cullis, P. R. (1990). Strategies for Optimizing Liposomal Doxorubicin. Journal of Liposome Research, 1(4), 463-480. doi:10.3109/08982109009036008

 

152 Madden, T. D., Janoff, A. S., & Cullis, P. R. (1990). Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol. Chemistry and Physics of Lipids, 52(3-4), 189-198. doi:10.1016/0009-3084(90)90114-7

 

151 Madden, T. D., Harrigan, P. R., Tai, L. C., Bally, M. B., Mayer, L. D., Redelmeier, T. E., Loughrey, H. C., Tilcock, C. P., Reinish, L. W., & Cullis, P. R. (1990). The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey. Chemistry and Physics of Lipids, 53(1), 37-46. doi:10.1016/0009-3084(90)90131-a

 

150 Loughrey, H. C., Wong, K. F., Choi, L. S., Cullis, P. R., & Bally, M. B. (1990). Protein-liposome conjugates with defined size distributions. Biochimica et biophysica acta, 1028(1), 73-81. doi:10.1016/0005-2736(90)90267-r

 

149 Loughrey, H. C., Choi, L. S., Cullis, P. R., & Bally, M. B. (1990). Optimized procedures for the coupling of proteins to liposomes. Journal of Immunological Methods, 132(1), 25-35. doi:10.1016/0022-1759(90)90394-B

 

148 Loughrey, H. C., Bally, M. B., Reinish, L. W., & Cullis, P. R. (1990). The binding of phosphatidylglycerol liposomes to rat platelets is mediated by complement. Journal of Thrombosis and Haemostasis, 64(1), 172-176

 

147 Lafleur, M., Cullis, P. R., Fine, B., & Bloom, M. (1990). Comparison of the orientational order of lipid chains in the L.alpha. and HII phases. Biochemistry, 29(36), 8325-8333. doi:10.1021/bi00488a018

 

146 Lafleur, M., Cullis, P. R., & Bloom, M. (1990). Modulation of the orientational order profile of the lipid acyl chain in the Lα phase. European Biophysics Journal, 19(2), 55-62. doi:10.1007/BF00185086

 

145 Lafleur, M., Bloom, M., & Cullis, P. R. (1990). Lipid polymorphism and hydrocarbon order. Biochemistry and Cell Biology, 68(1), 1-8. doi:10.1139/o90-001

 

144 Harrigan, P. R., Madden, T. D., & Cullis, P. R. (1990). Protection of liposomes during dehydration or freezing. Chemistry and Physics of Lipids, 52(2), 139-149. doi:10.1016/0009-3084(90)90157-M

 

143 Cullis, P. R., Tilcock, C. P., & Hope, M. J. (1990). Lipid Polymorphism. In Membrane Fusion. New York: Marcel Dekker, Inc.

 

142 Chakrabarti, A. C., Veiro, J. A., Wong, N., & Cullis, P. R. (1990). Use of transmembrane pH gradients and A23187 to produce dense iron liposomes. Biochemical Society Transactions, 18(5), 946-947. doi:10.1042/bst0180946  
141 Boni, L. T., Perkins, W. R., Minchey, S. R., Bolcsak, L. E., Gruner, S. M., Cullis, P. R., Hope, M. J., & Janoff, A. S. (1990). Polymorphic phase behavior of alpha-tocopherol hemisuccinate. Chemistry and Physics of Lipids, 54(3), 193-203. doi:10.1016/0009-3084(90)90012-G

 

140 Bally, M. B., Nayar, R., Masin, D., Hope, M. J., Cullis, P. R., & Mayer, L. D. (1990). Liposomes with entrapped doxorubicin exhibit extended blood residence times. Biochimica et biophysica acta, 1023(1), 133-139. doi:10.1016/0005-2736(90)90018-j

 

139 Bally, M. B., Nayar, R., Masin, D., Cullis, P. R., & Mayer, L. D. (1990). Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes. Cancer Chemotherapy and Pharmacology, 27(1), 13-19. doi:10.1007/BF00689270

 

138 Unger, E. C., MacDougall, P., Cullis, P. R., & Tilcock, C. P. (1989). Liposomal Gd-DTPA: effect of encapsulation on enhancement of hepatoma model by MRI. Magnetic Resonance Imaging, 7(4), 417-423. doi:10.1016/0730-725x(89)90491-8

 

137 Tilcock, C. P. S., Unger, E., Cullis, P. R., & MacDougall, P. (1989). Liposomal Gd-DTPA: preparation and characterization of relaxivity. Radiology, 171(1), 77-80. doi:10.1148/radiology.171.1.2928549

 

136 Tilcock, C. P. S., Dempsey, T., Cullis, P. R., & Fisher, D. (1989). The Partitioning of Liposomes of Defined Size and Composition. In D. Fisher & I. A. Sutherland (Eds.), Separations Using Aqueous Phase Systems: Applications in Cell Biology and Biotechnology (pp. 179-180). Boston, MA: Springer US.

 

135 Tilcock, C. P. S., Cullis, P. R., Dempsey, T., Youens, B. N., & Fisher, D. (1989). Aqueous two-phase polymer partitioning of lipid vesicles of defined size and composition. Biochimica et biophysica acta, 979(2), 208-214. doi:10.1016/0005-2736(89)90436-7

 

134 Tilcock, C. P. S., Chin, R., Veiro, J., Cullis, P. R., & Fisher, D. (1989). Detection of surface charge-related properties in model membrane systems by aqueous two-phase partition. Biochimica et biophysica acta, 986(1), 167-171. doi:10.1016/0005-2736(89)90287-3

 

133 Redelmeier, T. E., Mayer, L. D., Wong, K. F., Bally, M. B., & Cullis, P. R. (1989). Proton flux in large unilamellar vesicles in response to membrane potentials and pH gradients. Biophysical journal, 56(2), 385-393. doi:10.1016/S0006-3495(89)82684-0

 

132 Post, C. B., Ray, W. J., Jr., & Gorenstein, D. G. (1989). Time-dependent 31P saturation transfer in the phosphoglucomutase reaction. Characterization of the spin system for the Cd(II) enzyme and evaluation of rate constants for the transfer process. Biochemistry, 28(2), 548-558. doi:10.1021/bi00428a021

 

131 Parmar, Y. I., Sparks, D. L., Frohlich, J., Cullis, P. R., & Pritchard, P. H. (1989). Detection of vesicular lipoproteins in lecithin:cholesterol acyltransferase-deficient plasma by 1H-NMR spectroscopy. Journal of Lipid Research, 30(5), 765-771.

 

130 Ostro, M. J., & Cullis, P. R. (1989). Use of liposomes as injectable-drug delivery systems. American Journal of Hospital Pharmacy, 46(8), 1576-1587.  
129 Nayar, R., Hope, M. J., & Cullis, P. R. (1989). Generation of large unilamellar vesicles from long-chain saturated phosphatidylcholines by extrusion technique. Biochimica et biophysica acta, 986(2), 200-206. doi:10.1016/0005-2736(89)90468-9

 

128 Mayer, L. D., Tai, L. C., Ko, D. S., Masin, D., Ginsberg, R. S., Cullis, P. R., & Bally, M. B. (1989). Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice. Cancer Research, 49(21), 5922-5930.

 

127 Lafleur, M., Fine, B., Sternin, E., Cullis, P. R., & Bloom, M. (1989). Smoothed orientational order profile of lipid bilayers by 2H-nuclear magnetic resonance. Biophysical journal, 56(5), 1037-1041. doi:10.1016/S0006-3495(89)82749-3

 

126 Hope, M. J., Wong, K. F., & Cullis, P. R. (1989). Freeze-fracture of lipids and model membrane systems. Journal of Electron Microscopy Technique, 13(4), 277-287. doi:10.1002/jemt.1060130403

 

125 Hope, M. J., Redelmeier, T. E., Wong, K. F., Rodrigueza, W., & Cullis, P. R. (1989). Phospholipid asymmetry in large unilamellar vesicles induced by transmembrane pH gradients. Biochemistry, 28(10), 4181-4187. doi:10.1021/bi00436a009

 

124 Eastman, S. J., Wilschut, J., Cullis, P. R., & Hope, M. J. (1989). Intervesicular exchange of lipids with weak acid and weak base characteristics: influence of transmembrane pH gradients. Biochimica et biophysica acta, 981(2), 178-184. doi:10.1016/0005-2736(89)90026-6

 

123 Doerschuk, C. M., Gie, R. P., Bally, M. B., Cullis, P. R., & Reinish, L. W. (1989). Platelet distribution in rabbits following infusion of liposomes. Journal of Thrombosis and Haemostasis, 61(3), 392-396.

 

122 Cullis, P. R., Mayer, L. D., Bally, M. B., Madden, T. D., & Hope, M. J. (1989). Generating and loading of liposomal systems for drug-delivery applications. Advanced Drug Delivery Reviews, 3(3), 267-282. doi:10.1016/0169-409X(89)90024-0

 

121 Balazsovits, J. A. E., Mayer, L. D., Bally, M. B., Cullis, P. R., McDonell, M., Ginsberg, R. S., & Falk, R. E. (1989). Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin. Cancer Chemotherapy and Pharmacology, 23(2), 81-86. doi:10.1007/BF00273522

 

120 Unger, E., Needleman, P., Cullis, P., & Tilcock, C. (1988). Gadolinium-DTPA liposomes as a potential MRI contrast agent. Work in progress. Investigative radiology, 23(12), 928-932. doi:10.1097/00004424-198812000-00010

 

119 Tilcock, C. P. S., Sommerman, E. F., Molday, R. S., & Cullis, P. R. (1988). Magnetic Filtration of Vesicles Containing Iron-Dextran Particles. Journal of Liposome Research, 1, 137-150. doi:10.3109/08982108809035987

 

118 Tilcock, C. P. S., Cullis, P. R., & Gruner, S. M. (1988). Calcium-induced phase separation phenomena in multicomponent unsaturated lipid mixtures. Biochemistry, 27(5), 1415-1420. doi:10.1021/bi00405a004

 

117 Sternin, E., Fine, B., Bloom, M., Tilcock, C. P., Wong, K. F., & Cullis, P. R. (1988). Acyl chain orientational order in the hexagonal HII phase of phospholipid-water dispersions. Biophysical journal, 54(4), 689-694. doi:10.1016/S0006-3495(88)83004-2

 

116 Reinish, L. W., Bally, M. B., Loughrey, H. C., & Cullis, P. R. (1988). Interactions of liposomes and platelets. Thrombosis and haemostasis, 60(3), 518-523

 

115 Nayar, R., Tilcock, C. P. S., Hope, M. J., Cullis, P. R., & Schroit, A. J. (1988). N-Succinyldioleoylphosphatidylethanolamine: structural preferences in pure and mixed model membranes. Biochimica et biophysica acta, 937, 31-41. doi:10.1016/0005-2736(88)90224-6

 

114 Mayer, L. D., Wong, K. F., Menon, K., Chong, C., Harrigan, P. R., & Cullis, P. R. (1988). Influence of ion gradients on the transbilayer distribution of dibucaine in large unilamellar vesicles. Biochemistry, 27(6), 2053-2060. doi:10.1021/bi00406a036

 

113 Madden, T. D., Tilcock, C. P. S., Wong, K., & Cullis, P. R. (1988). Spontaneous vesiculation of large multilamellar vesicles composed of saturated phosphatidylcholine and phosphatidylglycerol mixtures. Biochemistry, 27(24), 8724-8730. doi:10.1021/bi00424a006

 

112 Janoff, A. S., Kurtz, C. L., Jablonski, R. L., Minchey, S. R., Boni, L. T., Gruner, S. M., Cullis, P. R., Mayer, L. D., & Hope, M. J. (1988). Characterization of cholesterol hemisuccinate and α-tocopherol hemisucccinate vesicles. Biochimica et biophysica acta, 941(2), 165-175. doi:10.1016/0005-2736(88)90177-0

 

111 Janoff, A. S., Boni, L. T., Popescu, M. C., Minchey, S. R., Cullis, P. R., Madden, T. D., Taraschi, T., Gruner, S. M., Shyamsunder, E., & Tate, M. W. (1988). Unusual lipid structures selectively reduce the toxicity of amphotericin B. Proceedings of the National Academy of Sciences of the United States of America, 85(16), 6122-6126. doi:10.1073/pnas.85.16.6122

 

110 Gruner, S. M., Tate, M. W., Kirk, G. L., So, P. T. C., Turner, D. C., Keane, D. T., Tilcock, C. P. S., & Cullis, P. R. (1988). X-ray diffraction study of the polymorphic behavior of N-methylated dioleoylphosphatidylethanolamine. Biochemistry, 27(8), 2853-2866. doi:10.1021/bi00408a029

 

109 Cullis, P. R., & Hope, M. J. (1988). Lipid Polymorphism, Lipid Asymmetry and Membrane Fusion. In S. Ohki, D. Doyle, T. D. Flanagan, S. W. Hui, & E. Mayhew (Eds.), Molecular Mechanisms of Membrane Fusion (pp. 37-51). Boston, MA: Springer US

 

108 Bally, M. B., Mayer, L. D., Loughrey, H., Redelmeier, T., Madden, T. D., Wong, K., Harrigan, P. R., Hope, M. J., & Cullis, P. R. (1988). Dopamine accumulation in large unilamellar vesicle systems induced by transmembrane ion gradients. Chemistry and Physics of Lipids, 47(2), 97-107. doi:10.1016/0009-3084(88)90078-3

 

107 Bally, M. B., Hope, M. J., Mayer, L. D., Madden, T. D., & Cullis, P. R. (1988). Novel Procedures for Generating and Loading Liposomal Systems (G. Gregoriadis Ed.): John Wiley & Sons Ltd

 

106 Wong, K. F., Parmar, Y. I., Mayer, L. D., Pritchard, P. H., & Cullis, P. R. (1987). Detection of protein-free lipoprotein analogues with an apolar lipid core by freeze-etch electron microscopy. Biochimica et biophysica acta, 921(2), 411-414. doi:10.1016/0005-2760(87)90044-0

 

105 Tilcock, C. P. S., & Cullis, P. R. (1987). Lipid Polymorphism. Annals of the New York Academy of Sciences, 492(1), 88-102. doi:10.1111/j.1749-6632.1987.tb48657.x

 

104 Sparks, D. L., Frohlich, J., Cullis, P. R., & Pritchard, P. H. (1987). Cholesteryl ester transfer activity in plasma measured by using solid-phase-bound high-density lipoprotein. Clinical Chemistry, 33(3), 390-393. doi:10.1093/clinchem/33.3.390

 

103 Rauch, J., Tannenbaum, H., Senécal, J. L., Janoff, A. S., Cullis, P. R., & Frojmovic, M. M. (1987). Polyfunctional properties of hybridoma lupus anticoagulant antibodies. The Journal of rheumatology. Supplement, 14 Suppl 13, 132-137  
102 Madden, T. D., Hope, M. J., & Cullis, P. R. (1987). Modelling the biological membrane. Biochemical Society Transactions, 15(1), 75

 

101 Loughrey, H., Bally, M. B., & Cullis, P. R. (1987). A non-covalent method of attaching antibodies to liposomes. Biochimica et biophysica acta, 901(1), 157-160. doi:10.1016/0005-2736(87)90267-7

 

100 Hope, M. J., & Cullis, P. R. (1987). Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. Journal of Biological Chemistry, 262(9), 4360-4366

 

99 Cullis, P. R., Hope, M. J., Bally, M. B., Madden, T. D., Mayer, L. D., & Janoff, A. S. (1987). Liposomes as Pharmaceuticals. New York: Marcel Dekker  
98 Tilcock, C. P. S., Cullis, P. R., Hope, M. J., & Gruner, S. M. (1986). Polymorphic phase behavior of unsaturated lysophosphatidylethanolamines: A phosphorus-31 NMR and x-ray diffraction study. Biochemistry, 25(4), 816-822. doi:10.1021/bi00352a013

 

97 Tilcock, C. P. S., Cullis, P. R., & Gruner, S. M. (1986). On the validity of 31P-NMR determinations of phospholipid polymorphic phase behaviour. Chemistry and Physics of Lipids, 40(1), 47-56. doi:10.1016/0009-3084(86)90061-7

 

96 Richards, R. L., Habbersett, R. C., Scher, I., Janoff, A. S., Schieren, H. P., Mayer, L. D., Cullis, P. R., & Alving, C. R. (1986). Influence of vesicle size on complement-dependent immune damage to liposomes. Biochimica et biophysica acta, 855(2), 223-230. doi:10.1016/0005-2736(86)90168-9

 

95 Rauch, J., Tannenbaum, M., Tannenbaum, H., Ramelson, H., Cullis, P. R., Tilcock, C. P. S., Hope, M. J., & Janoff, A. S. (1986). Hybridoma Lupus Anticoagulants Distinguish between Bilayer and Nonbilayer Phase Lipid Systems. Annals of the New York Academy of Sciences, 475(1), 366-369. doi:10.1111/j.1749-6632.1986.tb20896.x

 

94 Rauch, J., Tannenbaum, M., Tannenbaum, H., Ramelson, H., Cullis, P. R., Tilcock, C. P. S., Hope, M. J., & Janoff, A. S. (1986). Human hybridoma lupus anticoagulants distinguish between lamellar and hexagonal phase lipid systems. Journal of Biological Chemistry, 261(21), 9672-9677. Retrieved from http://www.jbc.org/content/261/21/9672.abstract

 

93 Mayer, L. D., Hope, M. J., & Cullis, P. R. (1986). Vesicles of variable sizes produced by a rapid extrusion procedure. Biochimica et biophysica acta, 858(1), 161-168. doi:10.1016/0005-2736(86)90302-0

 

92 Mayer, L. D., Bally, M. B., Hope, M. J., & Cullis, P. R. (1986). Techniques for encapsulating bioactive agents into liposomes. Chemistry and Physics of Lipids, 40(2-4), 333-345. doi:10.1016/0009-3084(86)90077-0

 

91 Mayer, L. D., Bally, M. B., & Cullis, P. R. (1986). Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient. Biochimica et biophysica acta, 857(1), 123-126. doi:10.1016/0005-2736(86)90105-7

 

90 Hope, M. J., Bally, M. B., Mayer, L. D., Janoff, A. S., & Cullis, P. R. (1986). Generation of multilamellar and unilamellar phospholipid vesicles. Chemistry and Physics of Lipids, 40(2), 89-107. doi:10.1016/0009-3084(86)90065-4

 

89 Cullis, P. R., Hope, M. J., & Tilcock, C. P. S. (1986). Lipid polymorphism and the roles of lipids in membranes. Chemistry and Physics of Lipids, 40(2), 127-144. doi:10.1016/0009-3084(86)90067-8

 

88 Cullis, P. R., de Kruijff, B., Verkleij, A. J., & Hope, M. J. (1986). Lipid polymorphism and membrane fusion. Biochemical Society Transactions, 14(2), 242-245. doi:10.1042/bst0140242  
87 Zhang, Y. Z., Capaldi, R. A., Cullis, P. R., & Madden, T. D. (1985). Orientation of cytochrome c oxidase molecules in the two populations of reconstituted vesicles resolved by column chromatography on DEAE-Sephacryl. Biochimica et biophysica acta, 808(1), 209-211. doi:10.1016/0005-2728(85)90045-3

 

86 Verkleij, A. J., Van Venetië, R., Leunissen-Bijvelt, J., De Kruijff, B., Hope, M., & Cullis, P. R. (1985). Membrane Fusion and Lipid Polymorphism. In F. Conti, W. E. Blumberg, J. de Gier, & F. Pocchiari (Eds.), Physical Methods on Biological Membranes and Their Model Systems (pp. 179-192). Boston, MA: Springer US

 

85 Mayer, L. D., Hope, M. J., Cullis, P. R., & Janoff, A. S. (1985). Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles. Biochimica et biophysica acta, 817(1), 193-196. doi:10.1016/0005-2736(85)90084-7

 

84 Mayer, L. D., Bally, M. B., Hope, M. J., & Cullis, P. R. (1985). Uptake of dibucaine into large unilamellar vesicles in response to a membrane potential. Journal of Biological Chemistry, 260(2), 802-808

 

83 Mayer, L. D., Bally, M. B., Hope, M. J., & Cullis, P. R. (1985). Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochimica et biophysica acta, 816(2), 294-302. doi:10.1016/0005-2736(85)90497-3

 

82 Madden, T. D., & Cullis, P. R. (1985). Preparation of reconstituted cytochrome oxidase vesicles with defined trans-membrane protein orientations employing a cytochrome c affinity column. Biochimica et biophysica acta, 808(2), 219-224. doi:10.1016/0005-2728(85)90002-7

 

81 Madden, T. D., Bally, M. B., Hope, M. J., Cullis, P. R., Schieren, H. P., & Janoff, A. S. (1985). Protection of large unilamellar vesicles by trehalose during dehydration: retention of vesicle contents. Biochimica et biophysica acta, 817(1), 67-74. doi:10.1016/0005-2736(85)90069-0

 

80 Hope, M. J., Bally, M. B., Webb, G., & Cullis, P. R. (1985). Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochimica et biophysica acta, 812(1), 55-65. doi:10.1016/0005-2736(85)90521-8

 

79 Gruner, S. M., Cullis, P. R., Hope, M. J., & Tilcock, C. P. S. (1985). Lipid Polymorphism: The Molecular Basis of Nonbilayer Phases. Annual Review of Biophysics and Biophysical Chemistry, 14(1), 211-238. doi:10.1146/annurev.bb.14.060185.001235

 

787 De Kruijff, B., Cullis, P. R., Verkleij, A. J., Hope, M. J., Van Echteld, C. J. A., & Taraschi, T. F. (1985). Lipid Polymorphism and Membrane Function. In A. N. Martonosi (Ed.), The Enzymes of Biological Membranes: Membrane Structure and Dynamics (Vol. 1, pp. 131-204). Boston, MA: Springer US

 

77 Cullis, P. R., Hope, M. J., & Taraschi, T. F. (1985). Modulation of lipid polymorphism by lipid-protein interactions. Progress in protein-lipid interactions, 1, 89-142  
76 Cullis, P. R., Hope, M. J., Nayar, R., & Tilcock, C. P. S. (1985). Roles of Phospholipids in Exocytosis (G. B. Ansell, G. Porcellati, & L. A. Horrocks Eds.). New York: Raven Press  
75 Cullis, P. R., Hope, M. J., Nayar, R., Bally, M. B., & Tilcock, C. P. S. (1985). Production of Large Unilamellar Vesicles by a Rapid Extrusion Procedure (G. B. Ansell, G. Porcellati, & L. A. Horrocks Eds.). Vol. 2: Physiological Roles  
74 Cullis, P. R., Hope, M. J., De Kruijff, B., Verkleij, A. J., & Tilcock, C. P. S. (1985). Structural Properties and Functional Roles of Phospholipids in Membranes (J. F. Kuo Ed.). Boca Raton: CRC Press  
73 Cullis, P. R., & Hope, M. J. (1985). Physical Properties and Functional Roles of Lipids in Membranes (D. E. Vance & J. E. Vance Eds.). Menlo Park: Benjamin/Cummings

 

72 Bally, M. B., Hope, M. J., Van Echteld, C. J. A., & Cullis, P. R. (1985). Uptake of safranine and other lipophilic cations into model membrane systems in response to a membrane potential. Biochimica et biophysica acta, 812(1), 66-76. doi:10.1016/0005-2736(85)90522-X

 

71 Verkleij, A. J., Leunissen-Bijvelt, L., De Kruijff, B., Hope, M. J., & Cullis, P. R. (1984). Non-Bilayer Structures in Membrane Fusion. In Ciba Foundation Symposium ‐ Cell Fusion (Vol. 103, pp. 45-59)  
70 Tilcock, C. P. S., Hope, M. J., & Cullis, P. R. (1984). Influence of cholesterol esters of varying unsaturation on the polymorphic phase preferences of egg phosphatidylethanolamine. Chemistry and Physics of Lipids, 35(4), 363-370. doi:10.1016/0009-3084(84)90078-1

 

69 Tilcock, C. P. S., Bally, M. B., Farren, S. B., Cullis, P. R., & Gruner, S. M. (1984). Cation-dependent segregation phenomena and phase behavior in model membrane systems containing phosphatidylserine: influence of cholesterol and acyl chain composition. Biochemistry, 23(12), 2696-2703. doi:10.1021/bi00307a025

 

68 Sommerman, E. F., Pritchard, P. H., & Cullis, P. R. (1984). 125I labelled inulin: a convenient marker for deposition of liposomal contents in vivo. Biochemical and Biophysical Research Communications, 122(1), 319-324. doi:10.1016/0006-291x(84)90477-7

 

67 Nayar, R., Mayer, L. D., Hope, M. J., & Cullis, P. R. (1984). Phosphatidic acid as a calcium ionophore in large unilamellar vesicle systems. Biochimica et biophysica acta, 777(2), 343-346. doi:10.1016/0005-2736(84)90438-3

 

66 Madden, T. D., Hope, M. J., & Cullis, P. R. (1984). Influence of vesicle size and oxidase content on respiratory control in reconstituted cytochrome oxidase vesicles. Biochemistry, 23(7), 1413-1418. doi:10.1021/bi00302a012

 

65 Madden, T. D., & Cullis, P. R. (1984). Detergent-induced solubilization of cytochrome c oxidase as detected in a novel reconstituted system. Journal of Biological Chemistry, 259(12), 7655-7658

 

64 Farren, S. B., Sommerman, E., & Cullis, P. R. (1984). Production of specifically deuterium labelled dioleoyl phospholipid species in gram quantities: A convenient synthesis of [C[11-2H2]oleic acid. Chemistry and Physics of Lipids, 34(3), 279-286. doi:10.1016/0009-3084(84)90062-8

 

63 Madden, T. D., Hope, M. J., & Cullis, P. R. (1983). Lipid requirements for coupled cytochrome oxidase vesicles. Biochemistry, 22(8), 1970-1974. doi:10.1021/bi00277a036  
62 Hope, M. J., Walker, D. C., & Cullis, P. R. (1983). Ca2+ and pH induced fusion of small unilamellar vesicles consisting of phosphatidylethanolamine and negatively charged phospholipids: a freeze fracture study. Biochemical and Biophysical Research Communications, 110(1), 15-22. doi:10.1016/0006-291x(83)91253-6

 

61 Farren, S. B., Hope, M. J., & Cullis, P. R. (1983). Polymorphic phase preferences of phosphatidic acid: A 31P and 2H NMR study. Biochemical and Biophysical Research Communications, 111(2), 675-682. doi:10.1016/0006-291x(83)90359-5

 

60 Cullis, P. R., De Kruijff, B., Hope, M. J., Verkleij, A. J., Nayar, R., Farren, S. B., Tilcock, C. P. S., Madden, T. D., & Bally, M. B. (1983). Structural Properties of Lipids and Their Functional Roles in Biological Membranes. In R. C. Aloia (Ed.), Concepts of Membrane Structure (pp. 39-81). New York: Academic Press  
59 Bally, M. B., Tilcock, C. P. S., Hope, M. J., & Cullis, P. R. (1983). Polymorphism of phosphatidylethanolamine-phosphatidylserine model systems: influence of cholesterol and Mg2+ on Ca2+-triggered bilayer to hexagonal (HII) transitions. Canadian Journal of Biochemistry and Cell Biology, 61, 346-352

 

58 Tilcock, C. P. S., & Cullis, P. R. (1982). The polymorphic phase behaviour and miscibility properties of synthetic phosphatidylethanolamines. Biochimica et biophysica acta, 684(2), 212-218. doi:10.1016/0005-2736(82)90008-6

 

57 Tilcock, C. P. S., Bally, M. B., Farren, S. B., & Cullis, P. R. (1982). Influence of cholesterol on the structural preferences of dioleoylphosphatidylethanolamine-dioleoylphosphatidylcholine systems: a phosphorus-31 and deuterium nuclear magnetic resonance study. Biochemistry, 21(19), 4596-4601. doi:10.1021/bi00262a013

 

56 Nayar, R., Schmid, S. L., Hope, M. J., & Cullis, P. R. (1982). Structural preferences of phosphatidylinositol and phosphatidylinositol-phosphatidylethanolamine model membranes. Influence of Ca2+ and Mg2+. Biochimica et biophysica acta, 688(1), 169-176. doi:10.1016/0005-2736(82)90592-2

 

55 Nayar, R., Hope, M. J., & Cullis, P. R. (1982). Phospholipids as adjuncts for calcium ion stimulated release of chromaffin granule contents: implications for mechanisms of exocytosis. Biochemistry, 21(19), 4583-4589. doi:10.1021/bi00262a011

 

54 Madden, T. D., & Cullis, P. R. (1982). Stabilization of bilayer structure for unsaturated phosphatidylethanolamines by detergents. Biochimica et biophysica acta, 684(1), 149-153. doi:10.1016/0005-2736(82)90061-X

 

53 Hemminga, M. A., & Cullis, P. R. (1982). 31P NMR studies of oriented phospholipid multilayers. Journal of Magnetic Resonance (1969), 47(2), 307-323. doi:10.1016/0022-2364(82)90122-6

 

52 De Kruijff, B., Nayar, R., & Cullis, P. R. (1982). 31P-NMR studies on phospholipid structure in membranes of intact, functionally-active, rat liver mitochondria. Biochimica et biophysica acta, 684(1), 47-52. doi:10.1016/0005-2736(82)90047-5

 

51 De Kruijff, B., Cullis, P. R., & Verkleij, A. J. (1982). Structural and Functional Aspects of Nonbilayer Lipids. In A. N. Martonosi (Ed.), Membranes and Transport: Volume 1 (pp. 43-49). Boston, MA: Springer US  
50 Tilcock, C. P. S., & Cullis, P. R. (1981). The polymorphic phase behavior of mixed phosphatidylserine-phosphatidylethanolamine model systems as detected by 31P-NMR. Effects of divalent cations and pH. Biochimica et biophysica acta, 641(1), 189-201. doi:10.1016/0005-2736(81)90583-6

 

49 Hornby, A. P., & Cullis, P. R. (1981). Influence of local and neutral anaesthetics on the polymorphic phase preferences of egg yolk phosphatidylethanolamine. Biochimica et biophysica acta, 647(2), 285-292. doi:10.1016/0005-2736(81)90256-X

 

48 Hope, M. J., & Cullis, P. R. (1981). The role of nonbilayer lipid structures in the fusion of human erythrocytes induced by lipid fusogens. Biochimica et Biophysica Acta 640(1), 82-90. doi:10.1016/0005-2736(81)90533-2

 

47 de Kruijff, B., Verkleij, A. J., van Echteld, C. J. A., Gerritsen, W. J., Noordam, P. C., Mombers, C., Rietveld, A., de Gier, J., Cullis, P. R., Hope, M. J., & Nayar, R. (1981). Non-bilayer Lipids and the Inner Mitochondrial Membrane. In H. G. Schweiger (Ed.), International Cell Biology 1980–1981: Papers Presented at the Second International Congress on Cell Biology Berlin (West), August 31 – September 5, 1980 (pp. 559-571). Berlin, Heidelberg: Springer Berlin Heidelberg

 

46 De Kruijff, B., Verkleij, A. J., Van Echteld, C. J. A., De Gier, J., & Cullis, P. R. (1981). Lipid Polymorphism and the Occurrence of Non-Bilayer Phases in Model and Biological Membranes, 1981 (B. e. al. Ed.): North Holland Publishing Co

 

45 Cullis, P. R., Farren, S. B., & Hope, M. J. (1981). 31P NMR Techniques and Membrane Lipid Structure: Implications for Mechanisms of Membrane Fusion. Canadian Journal of Spectroscopy, 26, 89-94  
44 Cullis, P. R. (1981). Functional Significance of Non-Bilayer Lipid Structure (S. Wolf & A. K. Murray Eds.). New York: Plenum Press  
43 Verkleij, A. J., Van Echteld, C. J. A., Gerritsen, W. J., Cullis, P. R., & De Kruijff, B. (1980). The lipidic particle as an intermediate structure in membrane fusion processes and bilayer to hexagonal HII transitions. Biochimica et biophysica acta, 600(3), 620-624. doi:10.1016/0005-2736(80)90465-4

 

42 Hope, M. J., & Cullis, P. R. (1980). Effects of divalent cations and pH on phosphatidylserine model membranes: A 31P NMR study. Biochemical and Biophysical Research Communications, 92(3), 846-852. doi:10.1016/0006-291X(80)90780-9

 

41 Farren, S. B., & Cullis, P. R. (1980). Polymorphism of phosphatidylglycerol-phosphatidylethanolamine model membrane systems: A 31P NMR study. Biochemical and Biophysical Research Communications, 97(1), 182-191. doi:10.1016/S0006-291X(80)80152-5

 

40 De Kruijff, B., Rietveld, A., & Cullis, P. R. (1980). 31P-NMR studies on membrane phospholipids in microsomes, rat liver slices and intact perfused rat liver. Biochimica et Biophysica Acta 600(2), 343-357. doi:10.1016/0005-2736(80)90438-1

 

39 De Kruijff, B., Morris, G. A., & Cullis, P. R. (1980). Application of 31P-NMR saturation transfer techniques to investigate phospholipid motion and organization in model and biological membranes. Biochimica et biophysica acta, 598(1), 206-211. doi:10.1016/0005-2736(80)90281-3

 

38 De Kruijff, B., Cullis, P. R., Verkleij, A. J., Vanechteld, C. J. A., Gerritsen, W. J., Mombers, C., Noordam, P. C., & Gier, J. D. (1980). Structural and functional roles of lipids in model and biological-membranes. European Journal of Cell Biology, 22(1), 217  
37 De Kruijff, B., Cullis, P. R., & Verkleij, A. J. (1980). Non-bilayer lipid structures in model and biological membranes. Trends in Biochemical Sciences, 5(3), 79-81. doi:10.1016/0968-0004(80)90074-2

 

36 De Kruijff, B., & Cullis, P. R. (1980). The influence of poly(l-lysine) on phospholipid polymorphism - Evidence that electrostatic polypeptide-phospholipid interactions can modulate bilayer/non-bilayer transitions. Biochimica et biophysica acta, 601, 235-240. doi:10.1016/0005-2736(80)90528-3

 

35 De Kruijff, B., & Cullis, P. R. (1980). Cytochrome c specifically induces non-bilayer structures in cardiolipin-containing model membranes. Biochimica et biophysica acta, 602(3), 477-490. doi:10.1016/0005-2736(80)90327-2

 

34 Cullis, P. R., Kruijff, B. d., Hope, M. J., Nayar, R., & Schmid, S. L. (1980). Phospholipids and membrane transport. Canadian Journal of Biochemistry, 58(10), 1091-1100. doi:10.1139/o80-147

 

33 Cullis, P. R., Hornby, A. P., & Hope, M. J. (1980). Effects of Anesthetics on Lipid Polymorphism (B. R. Fink Ed. Vol. 2: Progress in Anaesthesiology). New York: Raven Press

 

32 Cullis, P. R., & Hope, M. J. (1980). The bilayer stabilizing role of sphingomyelin in the presence of cholesterol. A 31P NMR study. Biochimica et biophysica acta, 597(3), 533-542. doi:10.1016/0005-2736(80)90225-4

 

31 Cullis, P. R., de Kruijff, B., Hope, M. J., Nayar, R., Rietveld, A., & Verkleij, A. J. (1980). Structural properties of phospholipids in the rat liver inner mitochondrial membrane. A 31P-NMR study. Biochimica et biophysica acta, 600(3), 625-635. doi:10.1016/0005-2736(80)90466-6

 

30 Burnell, E. E., Cullis, P. R., & de Kruijff, B. (1980). Effects of tumbling and lateral diffusion on phosphatidylcholine model membrane 31P-NMR lineshapes. Biochimica et biophysica acta, 603(1), 63-69. doi:10.1016/0005-2736(80)90391-0

 

29 Verkleij, A. J., Mombers, C., Gerritsen, W. J., Leunissen-Bijvelt, L., & Cullis, P. R. (1979). Fusion of phospholipid vesicles in association with the appearance of lipidic particles as visualized by freeze fracturing. Biochimica et Biophysica Acta (BBA) - Biomembranes, 555(2), 358-361. doi:10.1016/0005-2736(79)90175-5

 

28 Hope, M. J., & Cullis, P. R. (1979). The bilayer stability of inner monolayer lipids from the human erythrocyte. FEBS Letters, 107(2), 323-326. doi:10.1016/0014-5793(79)80399-3

 

27 Cullis, P. R., & Verkleij, A. J. (1979). Modulation of membrane structure by Ca2+ and dibucaine as detected by 31P NMR. Biochimica et Biophysica Acta, 552(3), 546-551. doi:10.1016/0005-2736(79)90200-1

 

26 Cullis, P. R., & De Kruijff, B. (1979). Lipid polymorphism and the functional roles of lipids in biological membranes. Biochimica et Biophysica Acta, 559(4), 399-420. doi:10.1016/0304-4157(79)90012-1

 

25 De Kruijff, B., van den Besselaar, A. M., Cullis, P. R., van den Bosch, H., & van Deenen, L. L. (1978). Evidence for isotropic motion of phospholipids in liver microsomal membranes. A 31P NMR study. Biochimica et Biophysica Acta, 514(1), 1-8. doi:10.1016/0005-2736(78)90072-x

 

24 Cullis, P. R., Verkleij, A. J., & Ververgaert, P. H. J. T. (1978). Polymorphic phase behaviour of cardiolipin as detected by 31P NMR and freeze-fracture techniques. Effects of calcium, dibucaine and chlorpromazine. Biochimica et Biophysica Acta (BBA), 513(1), 11-20. doi:10.1016/0005-2736(78)90107-4

 

23 Cullis, P. R., Van Dijck, P. W. M., De Kruijff, B., & De Gier, J. (1978). Effects of cholesterol on the properties of equimolar mixtures of synthetic phosphatidylethanolamine and phosphatidylcholine. A 31P NMR and differential scanning calorimetry study. Biochimica et Biophysica Acta, 513(1), 21-30. doi:10.1016/0005-2736(78)90108-6

 

22 Cullis, P. R., & Hope, M. J. (1978). Effects of fusogenic agent on membrane structure of erythrocyte ghosts and the mechanism of membrane fusion. Nature, 271(5646), 672-674. doi:10.1038/271672a0

 

21 Cullis, P. R., & De Kruijff, B. (1978). The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study. Biochimica et Biophysica Acta, 513(1), 31-42. doi:10.1016/0005-2736(78)90109-8

 

20 Cullis, P. R., & De Kruijff, B. (1978). Polymorphic phase behaviour of lipid mixtures as detected by 31P NMR. Evidence that cholesterol may destabilize bilayer structure in membrane systems containing phosphatidylethanolamine. Biochimica et Biophysica Acta, 507(2), 207-218. doi:10.1016/0005-2736(78)90417-0

 

19 Sim, E., & Cullis, P. R. (1977). 31P Nuclear magnetic resonance studies of cell membranes labelled with phosphonium phosphatidylcholine. FEBS Letters, 79(2), 340-344. doi:10.1016/0014-5793(77)80816-8

 

18 McLaughlin, A. C., Cullis, P. R., Hemminga, M. A., Brown, F. F., & Brocklehurst, J. (1977). Magnetic Resonance Studies of Model and Biological Membranes (R. A. Dwek, I. D. Campbell, R. E. Richards, & R. J. P. Williams Eds.): Academic Press  
17 Cullis, P. R., & McLaughlin, A. C. (1977). Phosphorus nuclear magnetic resonance studies of model and biological membranes. Trends in Biochemical Sciences, 2(9), 196-199.

 

16 Cullis, P. R., & Grathwohl, C. (1977). Hydrocarbon phase transitions and lipid-protein interactions in the erythrocyte membrane. A 31P NMR and fluorescence study. Biochimica et Biophysica Acta, 471(2), 213-226. doi:10.1016/0005-2736(77)90251-6

 

15 Cullis, P. R., De Kruijff, B., McGrath, A. E., Morgan, C. G., & Radda, G. K. (1977). Lipid Asymmetry, Clustering and Molecular Motion in Biological Membranes and Their Models. In S. Abrahamsson & I. Pascher (Eds.), Structure of Biological Membranes (pp. 389-407). Boston, MA: Springer US

 

14 De Kruijff, B., Cullis, P. R., Radda, G. K., & Richards, R. E. (1976). Phosphorus nuclear magnetic resonance of Acholeplasma laidlawii cell membranes and derived liposomes. Biochimica et Biophysica Acta, 419(3), 411-424. doi:10.1016/0005-2736(76)90255-8

 

13 De Kruijff, B., Cullis, P. R., & Radda, G. K. (1976). Outside-inside distributions and sizes of mixed phosphatidylcholine-cholesterol vesicles. Biochimica et Biophysica Acta, 436(4), 729-740. doi:10.1016/0005-2736(76)90402-8

 

12 Cullis, P. R., De Kruyff, B., & Richards, R. E. (1976). Factors affecting the motion of the polar headgroup in phospholipid bilayers. A 31P NMR study of unsonicated phosphatidylcholine liposomes. Biochimica et Biophysica Acta, 426(3), 433-446. doi:10.1016/0005-2736(76)90388-6

 

11 Cullis, P. R., & de Kruyff, B. (1976). 31P NMR studies of unsonicated aqueous dispersions of neutral and acidic phospholipids. Effects of phase transitions, p2H and divalent cations on the motion in the phosphate region of the polar headgroup. Biochimica et Biophysica Acta, 436(3), 523-540. doi:10.1016/0005-2736(76)90438-7

 

10 Cullis, P. R. (1976). Lateral diffusion rates of phosphatidylcholine in vesicle membranes: Effects of cholesterol and hydrocarbon phase transitions. FEBS Letters, 70(1), 223-228. doi:10.1016/0014-5793(76)80762-4

 

9 Cullis, P. R. (1976). Hydrocarbon phase transitions, heterogeneous lipid distributions and lipid—protein interactions in erythrocyte membranes. FEBS Letters, 68(2), 173-176. doi:10.1016/0014-5793(76)80430-9

 

8 Cullis, P. R. (1976). Electron paramagnetic resonance in inhomogeneously broadened systems: A spin temperature approach. Journal of Magnetic Resonance (1969), 21(3), 397-418. doi:10.1016/0022-2364(76)90044-5

 

7 Sim, E., Cullis, P. R., & Richards, R. E. (1975). Physical studies on phosphonium phosphatidylcholine. A unique [31P]phosphorus nuclear-magnetic-resonance probe for model and biological membranes. The Biochemical Journal, 151(3), 555-560. doi:10.1042/bj1510555

 

6 McLaughlin, A. C., Cullis, P. R., Hemminga, M. A., Hoult, D. I., Radda, G. K., Ritchie, G. A., Seeley, P. J., & Richards, R. E. (1975). Application of 31P NMR to model and biological membrane systems. FEBS Letters, 57(2), 213-218. doi:10.1016/0014-5793(75)80719-8

 

5 McLaughlin, A. C., Cullis, P. R., Berden, J. A., & Richards, R. E. (1975). 31P NMR of Phospholipid membranes: Effects of chemical and anisotropy at high magnetic field strengths. Journal of Magnetic Resonance (1969), 20(1), 146-165. doi:10.1016/0022-2364(75)90162-6

 

4 De Kruijff, B., Cullis, P. R., & Radda, G. K. (1975). Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphatidylcholine liposomes. Biochimica et Biophysica Acta, 406(1), 6-20. doi:10.1016/0005-2736(75)90038-3

 

3 Cullis, P. R., & Marko, J. R. (1975). Electron paramagnetic resonance properties of n-type silicon in the intermediate impurity-concentration range. Physical Review B, 11(11), 4184-4200. doi:10.1103/PhysRevB.11.4184

 

2 Berden, J. A., Cullis, P. R., Hoult, D. I., McLaughlin, A. C., Radda, G. K., & Richards, R. E. (1974). Frequency dependence of 31P NMR linewidths in sonicated phospholipid vesicles: Effects of chemical shift anisotropy. FEBS Letters, 46(1), 55-58. doi:10.1016/0014-5793(74)80333-9

 

1 Cullis, P. R., & Marko, J. R. (1970). Determination of the Donor Pair Exchange Energy in Phosphorus-Doped Silicon. Physical Review B, 1(2), 632-637. doi:10.1103/PhysRevB.1.632

 

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