CURRENT CULLIS LAB MEMBERSResearch Associates |
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Igor Zhigaltsev, PhDMy areas of interest include the design, formulation, physicochemical characterization and in vitro and in vivo evaluation of liposome-based drug forms. Specific methods and techniques used in my research include: preformed vesicle approach, remote loading techniques, freeze-fracture and transmission electron microscopy, evaluation of in vivo pharmacokinetics of liposomal drugs. phone: 604-822-4955 |
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Genc Basha, MD, PhDPhD Tumor Biology, Katholieke Universiteit Leuven. Leuven, Belgium.
The focus of my research includes the mechanism of uptake and intracellular trafficking of liposomal nanoparticles and gene targeting in antigen presenting cells (DCs) and tumor cells.
e-mail: gbasha@mail.ubc.ca phone: 602-822-2649 |
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Chris Tam, PhDBSc Biochemistry, McGill University. Montreal, QC. PhD Cell Biology, University of Alberta. Edmonton, AB.
My research focuses on selectively targeting liposomal nanoparticulate (LN) siRNA formulations to particular cells using small ligands.
e-mail: tam7@mail.ubc.ca phone: 604-822-6263 |
Post Doctoral Fellows |
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Paulo Lin, PhDBSc Biochemistry, University of British Columbia. Vancouver, BC. PhD Biochemistry and Molecular Biology, University of British Columbia. Vancouver, BC.
My research interests focus on the mechanisms by which liposome nanoparticles (LN) gain entry into the cell. Using both biological and biochemical means I am interested in dissecting and improving the cytoplasmic delivery of LN in vivo.
e-mail:paulol@mail.ubc.ca phone: 604-822-4955 |
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Chen Wan, PhDBSc Biochemistry, University of Science and Technology of China. Hefei, China PhD Biochemistry, University of Virginia. Charlottesville, VA, USA.
e-mail: cw7h@mail.ubc.ca phone: 604-822-4955 |
Technicians |
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Vanessa Sung, BA&ScBA and Sc Cellular and Molecular Biology, McGill University, Montreal, QC
e-mail: vsung@mail.ubc.ca phone: 604-822-6263 |
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Cayetana Schluter, MScLab Manager
e-mail: cayetana@mail.ubc.ca phone: 604-822-6263 |
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Nathan Belliveau, BAScBASc Nanotechnology Engineering, University of Waterloo, Waterloo, ON.
My project focuses on developing a new method for producing LNs and encapsulating siRNA based drugs.
e-mail: nbelliveau@precisionnanosystems.com phone: 604-822-4955 |
Yan Liu, BScTechnician
e-mail: yliu100@mail.ubc.ca phone: 604-822-4955 |
Graduate Students |
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Alex Leung, BSc, PhD CandidateBSc Biochemistry, University of Calgary, Calgary, AB.
My project involves the characterization of lipids designed for the delivery of siRNA and the interaction of LN with cellular membranes. In my research biophysical techniques such as NMR are used as a tool to understand the behaviour of lipid membranes at the physical level. Our findings will enable us to rationally design novel lipids with improved transfection efficiencies and therapeutic potential.
e-mail: akkleung@interchange.ubc.ca phone: 604-822-2649 |
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Sam Chen, BScBSc Biochemistry, University of British Columbia, Vancouver, BC.
My project focuses on developing a new functional knockdown assay.
e-mail: schen03@interchange.ubc.ca phone: 604-822-6263 |
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Justin Lee, BSc, PhD CandidateBSc Biochemistry, University of Calgary, Calgary, AB.
My project focuses on the knockdown of the androgen receptor using liposomal nanoparticles (LNs) in advanced prostate cancer. Small interfering RNA (siRNA) directed against the androgen receptor will be encapsulated into LNs to allow for specific targeting to the prostate. The project is in collaboration with Dr. Paul S. Rennie (The Prostate Centre @ Vancouver General Hospital).
e-mail: justlee@interchange.ubc.ca phone: 604-822-4955 |
| Honours/Rotation Students | |
Ann SunBiochemistry Honours Student
Antibody conjugation (supervised by Dr. Paulo Lin)
e-mail: annsun89@gmail.com phone: 604-822-4955
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Jocelyn QuickBiochemistry Honours Student
LNP screening (supervised by Dr. Chris Tam)
e-mail: joslynquick@gmail.com phone: 604-822-4955 |
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Ruiwei JiangRotation Student (Supervised by Dr. Chris Tam)
e-mail: ruiwei@interchange.ubc.ca phone: 604-822-4955 |